Knoch, T. A. Dreidimensionale Organisation von Chromosomen-Domänen in Simulation und Experiment. (Three-dimensional organization of chromosome domains in simulation and experiment.) Diploma Thesis, Faculty for Physics and Astronomy, Ruperto-Carola University, Heidelberg, Germany, 1998 and TAK Press, Tobias A. Knoch, Mannheim, Germany, ISBN 3-00-010685-5, 2003.

Knoch, T. A., Münkel, C. & Langowski, J. Three-dimensional organization of chromosome territories and the human cell nucleus - about the structure of a self replicating nano fabrication site. Foresight Institute - Article Archive, Foresight Institute, Palo Alto, CA, USA, http://www.foresight.org ,1-6, 1998.

Knoch, T. A., Münkel, C. & Langowski, J. Three-Dimensional Organization of Chromosome Territories and the Human Interphase Nucleus. High Performance Scientific Supercomputing, editor Wilfried Juling, Scientific Supercomputing Center (SSC) Karlsruhe, University of Karlsruhe (TH), 27-29, 1999.

Knoch, T. A., Münkel, C. & Langowski, J. Three-dimensional organization of chromosome territories in the human interphase nucleus. High Performance Computing in Science and Engineering 1999, editors Krause, E. & Jäger, W., High-Performance Computing Center (HLRS) Stuttgart, University of Stuttgart, Springer Berlin-Heidelberg-New York, ISBN 3-540-66504-8, 229-238, 2000.

Bestvater, F.*, Knoch, T. A.*, Langowski, J. & Spiess, E. GFP-Walking: Artificial construct conversions caused by simultaneous cotransfection. BioTechniques 32(4), 844-854, 2002. Gil-Parado, S., Fernández-Montalván, A., Assfalg-Machleidt, I., Popp, O., Bestvater, F., Holloschi, A., Knoch, T. A., Auerswald, E. A., Welsh, K., Reed, J. C., Fritz, H., Fuentes-Prior, P., Spiess, E., Salvesen, G. & Machleidt, W. Ionomycin-activated calpain triggers apoptosis: A probable role for Bcl-2 family members. J. Biol. Chem. 277(30), 27217-27226, 2002.

Knoch, T. A. Approaching the three-dimensional organization of the human genome: structural-, scaling- and dynamic properties in the simulation of interphase chromosomes and cell nuclei, vilong-range correlations in complete genomes, in vivo quantification of the chromatin distribution, construct conversions in simultaneous co-transfections. Dissertation, Ruperto-Carola University, Heidelberg, Germany, and TAK Press, Tobias A. Knoch, Mannheim, Germany, ISBN 3-00-009959-X, ISBN 3-00-009960-3, 2002. [download]

Westphal, G., van den Berg-Stein, S., Braun, K., Knoch, T. A., Dümmerling, M., Langowski, J., Debus, J. & Friedrich, E. Detection of the NGF receptors TrkaA and p75NTR and effect of NGF on the growth characteristics of human tumor cell lines. J. Exp. Clin. Canc. Res. 21(2), 255-267, 2002.

Westphal, G., Niederberger, E., Blum, C., Wollman, Y., Knoch, T. A., Dümmerling, M., Rebel, W., Debus, J. & Friedrich, E. Erythropoietin Receptor in Human Tumor Cells: Expression and Aspects Regarding Functionality. Tumori 88(2), 150-159, 2002.

Gil-Parado, S., Popp, O., Knoch, T. A., Zahler, S., Bestvater, F., Felgenträger, M., Holoshi, A., Fernández-Montalván, A., Auerswald, E. A., Fritz, H., Fuentes-Prior, P., Machleidt, W. & Spiess, E. Subcellular localization and subunit interactions of over-expressed human µ-calpain. J. Biol. Chem. 278(18), 16336-15346, 2003.

Knoch, T. A. Towards a holistic understanding of the human genome by determination and integration of its sequential and three-dimensional organization. High Performance Computing in Science and Engineering 2003, editors Krause, E., Jäger, W. & Resch, M., High-Performance Computing Center (HLRS) Stuttgart, University of Stuttgart, Springer Berlin-Heidelberg-New York, ISBN 3-540-40850-9, 421-440, 2003.

Wachsmuth, M., Weidemann, T., Müller, G., Urs W. Hoffmann-Rohrer, Knoch, T. A., Waldeck, W. & Langowski, J. Analyzing intracellular binding and diffusion with continuous fluorescence photobleaching. Biophys. J. 84(5), 3353-3363, 2003.

Weidemann, T., Wachsmuth, M., Knoch, T. A., Müller, G., Waldeck, W. & Langowski, J. Counting nucleosomes in living cells with a combination of fluorescence correlation spectroscopy and confocal imaging. J. Mol. Biol. 334(2), 229-240, 2003.

Fejes Tóth, K., Knoch, T. A., Wachsmuth, M., Frank-Stöhr, M., Stöhr, M., Bacher, C. P., Müller, G. & Rippe, K. Trichostatin A induced histone acetylation causes decondensation of interphase chromatin. J. Cell Science 177, 4277-4287, 2004.

Ermler, S.*, Krunic, D.*, Knoch, T. A., Moshir, S., Mai, S., Greulich-Bode, K. M. & Boukamp, P. Cell cycle-dependent 3D distribution of telomeres and telomere repeat-binding factor 2 (TRF2) in HaCaT and HaCaT-myc cells. Europ. J. Cell Biol. 83(11-12), 681-690, 2004.

Kost, C., Gama de Oliveira, E., Knoch, T. A. & Wirth, R. Spatio-temporal permanence and plasticity of foraging trails in young and mature leaf-cutting ant colonies (Atta spp.). J. Trop. Ecol. 21(6), 677-688, 2005.

Winnefeld, M., Grewenig, A., Schnölzer, M., Spring, H., Knoch, T. A., Gan, E. C., Rommelaere, J. & Cziepluch, C. Human SGT interacts with BAG-6/Bat-3/Scythe and cells with reduced levels of either protein display persistence of few misaligned chromosomes and mitotic arrest. Exp. Cell Res. XX, XX-XX, 2006. (in press).

Relevant Patents
Knoch, T. A., Waldeck, W., Müller, G., Alonso, A. & Langowski, J. DNA-Sequenz und Verfahren zur in vivo Markierung und Analyse von DNA/Chromatin in Zellen. German Patent Application 10013204.9-44 and International Patent Application PCT/DE01/01044.

Bestvater, F.*, Knoch, T. A.*, Spiess, E. Nachweisverfahren für homologe Rekombinationsereignisse. German Patent Application 10116826.8 and International Patent Application PCT/DE02/01207.

Knoch, T. A., Göcker, M. & Lohner, R. Methods for the analysis, classification and/or tree construction of sequences using correlation analysis. US Patent Application 60/436.056 and International Patent Application PCT/EP03/14854.

*: Shared first authorship due to equal contribution.