Project number 36
Clinical epidemiology of cardiovascular diseases
In the past decades, significant improvement has been achieved in the management and outcome of patients with cardiovascular disease (CVD). Despite these developments, CVD still is a major cause of the loss of healthy years in The Netherlands: the annual number of fatal events is as high as 40,000. The burden of CVD is expected to increase in the decades ahead, and it is crucial to develop and improve CVD risk prediction instruments, and implement appropriate preventive and therapeutic measures. Traditionally, the assessment of CVD risk is based on global risk models. However, these models fall short, as they do not utilize contemporary knowledge on the pathophysiology of CVD. Project 36 Clinical epidemiology of cardiovascular diseases is designed to improve CVD risk assessment and risk reduction. Several concepts are currently studied: (multiple) CVD biomarkers, repeated biomarker assessment, cardiac imaging, dynamic risk modelling and simulation risk modelling.
| Principal Investigator | H Boersma |
| Co-Investigators | KM Akkerhuis, RT van Domburg, I Kardys, J van der Lei, EM van Mulligen, SS Pedersen, N van der Putten, PW Serruys, ML Simoons, EW Steyerberg, JJM Takkenberg |
| PhD candidates | LC Battes, SPM de Boer, N van Boven, JM Cheng, NLM Damen, M de Mulder, RM Oemrawsingh, M Sunamura, LC van Vark |