Osterhaus, Ab

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Ab Osterhaus is the Head of the Institute of Virology of the Erasmus Medical Center Rotterdam with currently about 100 employees, including post-docs, MDs, and PhD students. He has a broad experience in leading research projects in the fields of vaccine development and immunopathogenesis of virus infections of man and animals. He holds many editorial appointments for scientific journals, is the holder of several patents, has been the mentor of more than 50 PhD students and from 1980 onwards has held over 50 consultantships. Over the last 25 years, Prof. Osterhaus has identified more than a dozen "new" viral pathogens. He is author of more than 580 peer reviewed scientific papers.

Present positions
Professor of Virology, Erasmus MC, Rotterdam
Head of the Department of Virology, Erasmus MC, Rotterdam
Director National Influenza Center (NIC), Rotterdam
Director WHO Global Reference Laboratory for Measles
Head WHO National Reference Laboratory for Measles and Rubella with RIVM Bilthoven
Director WHO Collaborating Centre for Arboviruses and Haemorrhagic Fever Reference and Research
Chairman of the Postgraduate School Molecular Medicine Erasmus MC
Member of the Graduate School Erasmus MC
Professor of Wildlife Virology and virus discovery, University Utrecht

Department of Virology website  


Key publications

Drosten, C., Gunther, S., Preiser, W., Van der Werf, S., Brodt, H.-R., Becker, S., Rabenau, H., Panning, M., Kolesnikova, L., Fouchier, R.A.M., Berger, A., Burguière, A.-M., Cinatl, J., Eickmann, M., Escriou, N., Grywna, K., Kramme, S., Manuguerra, J.-C., Muller, S., Rickerts, V., Stürmer, M., Vieth, S., Klenk, H.-D., Osterhaus, A.D.M.E., Schmitz, H., Doerr, H.W (2003)
Identification of a novel coronavirus in patients with severe acute respiratory syndrome
New England Journal of Medicine 48:1967-1976

Rota, P.A., Oberste, M.S., Monroe, S.S., Nix, W.A., Campagnoli, R., Icenogle, J.P., Peñaranda, S., Bankamp, B., Maher, K., Chen, M.-H., Tong, S., Tamin, A., Lowe, L., Frace, M., DeRisi, J.L., Chen, Q., Wang, D., Erdman, D.D., Peret, T.C.T., Burns, C., Ksiazek, T.G., Rollin, P.E., Sanchez, A., Liffick, S., Holloway, B., Limor, J., McCaustland, K., Olsen-Rasmussen, M., Fouchier, R., Günther, S., Osterhaus, A.D.H.E., Drosten, C., Pallansch, M.A., Anderson, L.J., Bellini, W.J. (2003)
Characterization of a novel coronavirus associated with severe acute respiratory syndrome
Science 300:1394-1399

Van Den Hoogen, B.G., De Jong, J.C., Groen, J., Kuiken, T., De Groot, R., Fouchier, R.A.M., Osterhaus, A.D.M.E. (2001)
A newly discovered human pneumovirus isolated from young children with respiratory tract disease
Nature Medicine 7:719-724

Claas, E.C.J., Osterhaus, A.D.M.E., Van Beek, R., De Jong, J.C., Rimmelzwaan, G.F., Senne, D.A., Krauss, S., Shortridge, K.F., Webster, R.G. (1998)
Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus
Lancet 351:472-477

Klein, M.R., Van Baalen, C.A., Holwerda, A.M., Kerkhof Garde, S.R., Bende, R.J., Keet, I.P.M., Eeftinck-Schattenkerk, J.-K.M., Osterhaus, A.D.M.E., Schuitemaker, H., Miedema, F. (1995)
Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: A longitudinal analysis of rapid progressors and long-term asymptomatics
Journal of Experimental Medicine 181:1365-1372

Fouchier, R.A.M., Kuiken, T., Schutten, M., Van Amerongen, G., Van Doornum, G.J.J., Van Den Hoogen, B.G., Peiris, M., Lim, W., Stöhr, K., Osterhaus, A.D.M.E. (2003)
Koch's postulates fulfilled for SARS virus
Nature 423:240

Hayden, F.G., Osterhaus, A.D.M.E., Treanor, J.J., Fleming, D.M., Aoki, F.Y., Nicholson, K.G., Bohnen, A.M., Hirst, H.M., Keene, O., Wightman, K. (1997)
Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenzavirus infections
New England Journal of Medicine 337:874-880

Kuiken, T., Fouchier, R.A.M., Schutten, M., Rimmelzwaan, G.F., Van Amerongen, G., Van Riel, D., Laman, J.D., De Jong, T., Van Doornum, G., Lim, W., Ling, A.E., Chan, P.K.S., Tam, J.S., Zambon, M.C., Gopal, R., Drosten, C., Van Der Werf, S., Escriou, N., Manuguerra, J.-C., Stöhr, K., Peiris, J.S.M., Osterhaus, A.D.M.E. (2003)
Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome
Lancet 362:263-270

Fouchier, R.A.M., Munster, V., Wallensten, A., Bestebroer, T.M., Herfst, S., Smith, D., Rimmelzwaan, G.F., Olsen, B., Osterhaus, A.D.M.E. (2005)
Characterization of a novel influenza A virus hemagglutinin subtype (H16) obtained from black-headed gulls
Journal of Virology 79:2814-2822

Nicholson, K.G., Aoki, F.Y., Osterhaus, A.D.M.E., Trottier, S., Carewicz, O., Mercier, C.H., Rode, A., Kinnersley, N., Ward, P. (2000)
Efficacy and safety of oseltamivir in treatment of acute influenza: A randomised controlled trial
Lancet 355:1845-1850