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Facilities

Mass spectrometry, Microarray, Optical Imaging, mouse transgenics and FACS.

The Department of Cell Biology is part of the Cluster of Medical Genetics and has access to a number of facilities.

  • The Mass spectrometry facility, headed by Dr. Jeroen Demmers, is in the Erasmus Centre of Biomics. Proteins (and protein-modifications) from our purifications are identified within days, using the latest, ultra-sensitive, equipment. This facility, combined with the biochemical expertise within the department, provides an ideal environment for the identification and characterization of protein interactions.
  • The Microarray facility, headed by Ir. Wilfred van IJcken, is in the genomics section of the Erasmus Centre of Biomics. It provides services and expertise for gene expression analysis and a number of other genome-related techniques, which will save time in your research and provides easy opportunity for new research venues.
  • In the applied Optical Imaging Centre, we have access to the latest microscopy technology and expertise, including a 4Pi microscope for high optical resolution, a 2-photon microscope, and several confocal microscopes, especially adapted for different aspects of FRAP, FLIP and FRET technology.
  • In our mouse transgenics facility, we use the latest techniques to make mouse (conditional) knock-outs and knock-ins and derive (ES) cell lines and other cells from mice.
  • Our Fluorescence-Activated Cell Sorter (FACS) allows rapid separation of live and fixed cells, based on fluorescence (by immunochemistry and fluorescent proteins such as GFP).
  •  Our work is supported by the Erasmus Center for Bioinformatics , which supplies experience and software for the processing and interpretation of complex data sets. 
  • Computer hardware and software in the department is supported by the IT support desk