Professor David T. Scadden, MD

Gerald and Darlene Jordan Professor of Medicine, Harvard University
Co-Chair, Department of Stem Cell and Regenerative Biology, Harvard University
Co-Director, Harvard Stem Cell Institute
Director, MGH Center for Regenerative Medicine
Chief, Hematologic Malignancies
MGH Cancer Center
CPZN - Room 4265A, 185 Cambridge Street
Boston, MA 02114
Tel: 617-726-5615
Fax: 617-724-2662
email:scadden.david@mgh.harvard.edu

The MGH Center for Regenerative Medicine is dedicated to understanding how tissues are formed and may be repaired. Our primary goal is to develop novel therapies to regenerate damaged tissues and overcome debilitating chronic disease. The success of this regenerative medicine effort requires a cohesive team of scientists and clinicians with diverse areas of expertise, but with a shared mission and dedication to the larger goal. The focus of my laboratory is stem cell biology. We have a particular interest in the regulation of the cell cycle within the stem cell compartment and have identified differentiation stage specific roles for cyclin dependent kinase inhibitors. In addition, we are interested in the microenvironmental niche as a physiologic regulator of stem cell behavior. Each of these is addressed with a particular emphasis on how they might be targeted to human health.