medewerkers R&D

maak kennis met onze medewerkers van de R&D

 

prof. dr. A. van Belkum
unithoofd R&D, moleculair bioloog
e-mail: a.vanbelkum@erasmusmc.nl

 

dr. I.A.J.M. Bakker-Woudenberg

medisch bioloog

e-mail : i.bakker-woudenberg@erasmusmc.nl  

 

responsibilities

  • Research and supervising research projects
  • Field of research: Antibiotic pharmacodynamics and antibiotic delivery systems in infectious diseases in relation to therapeutic efficacy and emergence of antibiotic resistance
  • Teaching and curriculum development in Medical Microbiology and Infectious Diseases
  • Management  

current research topics

  • Tuberculose, targeted drug delivery to shorten treatment duration and to prevent resistance and latency, role of endemic strains.
  • Fungal infections, innovative therapeutic intervention in invasive pulmonary aspergillosis in the immunocompromised host.
  • Factors involved in the enhancement of mutations leading to extended-spectrum-beta-lactamase resistance in Klebsiella pneumoniae.
  • New antibiotics to fight antimicrobial resistance in bacterial and fungal infections.  Protective human antibodies against antibiotic-resistant Klebsiella pneumoniae and Staphylococcus aureus as an alternative non-antibiotic-based antimicrobial strategy.
  • Beta-lactam resistance in Pseudomonas aeruginosa, factors important to the emergence of resistance, mechanisms of resistance and prevention. 

 

dr. W.B. van Leeuwen
moleculair bioloog
e-mail: w.vanleeuwen@erasmusmc.nl

   

dr. J.P. Hays
postdoctoral molecular microbiologist
e-mail: j.hays@erasmusmc.nl

 

research

  • Currently researching the population structure and virulence characteristics of the bacterium Moraxella catarrhalis, as well as the molecular epidemiology of antibiotic resistance genes and cassettes in Enterococci and Enterobacteriaceae (ESBLs).      

2007 – 2009

Principal investigator and co-applicant for an EU-funded FP6 project  “Novel Prevention and Treatment Strategies for Otitis Media through the Comprehensive Identification of Antigenic Proteins”. Project  No. – 037653 (OMVAC).

2006 – 2009

Principal investigator for an EU-funded FP6 project  “Role of Mobile Genetic Elements in the Spread of Antimicrobial Drug Resistance ”. Project  No. 018705 (DRESP2).

2003 – 2005

Principal investigator for a SOPHIA foundation (SOPHIA stichting) project “Development of eradication methods for Moraxella catarrhalis , a major cause of otitis media in children”.


other responsibilities 

  • Unit R&D contact person for advice relating to work, environment and quality issues (Arbo, Milieu en Kwaliteit (AMKer))
  • Unit R&D contact person for advice regarding the use of laboratories for genetically modified organisms