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Cappellen, Gert van

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Gert van CappellenGert van Cappellen obtained his applied science degree (Dutch HTS diploma) in chemistry in 1980. In 1983 he started as a technician at Erasmus University Rotterdam (and later, Erasmus MC). Having worked for a while in the Anatomy department, where he investigated sex development in rats, in 1990 he joined the Erasmus MC department of Reproduction and Development (at the time known as Endocrinology and Reproduction). In May 1998, he obtained his PhD with his research project on ovarian follicle development in rats.

Besides computer support and research on apoptosis, from 1996 onwards Gert specialized in the development of confocal and other types of advanced microscopy within Erasmus MC, in collaboration with fellow researchers. At present, he trains and supports users, while taking care of the maintenance of existing and the purchase of new equipment, setting up new techniques and applying them to current research projects. In this way, he gives guidance to a number of researchers.

Gert van Cappellen is the initiator and chairman of the Erasmus MC - Optical Imaging Centre (OIC). Co-founders are: Adriaan Houtsmuller, Timo ten Hagen, Niels Galjart and Wim Vermeulen. In 2006 the OIC was reduced to three people: Adriaan Houtsmuller, Alex Nigg and Gert van Cappellen. The OIC remains one of the largest optical imaging centres for research within the Netherlands.

Gert van Cappellen leads a returning course on Laser Scanning Microscopy. Every year, he organizes the PhD-course ‘In Vivo Imaging’.

 

Erasmus MC - Optical Imaging Centre (OIC)

 

Publications:

Dragestein, K.A., W.A. van Cappellen, J. van Haren, G.D. Tsibidis, A. Akhmanova, T.A. Knoch, F. Grosveld, and N. Galjart (2008)
Dynamic behavior of GFP-CLIP-170 reveals fast protein turnover on microtubule plus ends
J Cell Biol 180(4): p. 729-37.

Dinant, C., M. de Jager, J. Essers, W.A. van Cappellen, R. Kanaar, A.B. Houtsmuller, and W. Vermeulen
Activation of multiple DNA repair pathways by sub-nuclear damage induction methods
J Cell Sci, 2007. 120(Pt 15): p. 2731-40.

Zotter, A., M.S. Luijsterburg, D.O. Warmerdam, S. Ibrahim, A. Nigg, W.A. van Cappellen, J.H. Hoeijmakers, R. van Driel, W. Vermeulen, and A.B. Houtsmuller
Recruitment of the nucleotide excision repair endonuclease XPG to sites of UV-induced dna damage depends on functional TFIIH
Mol Cell Biol, 2006. 26(23): p. 8868-79.

Hut, H.M., K.P. Rembacz, M.A. van Waarde, W. Lemstra, W.A. van Cappellen, H.H. Kampinga, and O.C. Sibon
Dysfunctional BRCA1 is only indirectly linked to multiple centrosomes
Oncogene, 2005. 24(51): p. 7619-23.

Essers, J., W.A. van Cappellen, A.F. Theil, E. van Drunen, N.G. Jaspers, J.H. Hoeijmakers, C. Wyman, W. Vermeulen, and R. Kanaar
Dynamics of relative chromosome position during the cell cycle
Mol Biol Cell, 2005. 16(2): p. 769-75.

Essers, J., A.F. Theil, C. Baldeyron, W.A. van Cappellen, A.B. Houtsmuller, R. Kanaar, and W. Vermeulen
Nuclear dynamics of PCNA in DNA replication and repair
Mol Cell Biol, 2005. 25(21): p. 9350-9.

Cheng, C., R. van Haperen, M. de Waard, L.C. van Damme, D. Tempel, L. Hanemaaijer, G.W. van Cappellen, J. Bos, C.J. Slager, D.J. Duncker, A.F. van der Steen, R. de Crom, and R. Krams
Shear stress affects the intracellular distribution of eNOS: direct demonstration by a novel in vivo technique
Blood, 2005. 106(12): p. 3691-8.

Akhmanova, A., A.L. Mausset-Bonnefont, W. van Cappellen, N. Keijzer, C.C. Hoogenraad, T. Stepanova, K. Drabek, J. van der Wees, M. Mommaas, J. Onderwater, H. van der Meulen, M.E. Tanenbaum, R.H. Medema, J. Hoogerbrugge, J. Vreeburg, E.J. Uringa, J.A. Grootegoed, F. Grosveld, and N. Galjart
The microtubule plus-end-tracking protein CLIP-170 associates with the spermatid manchette and is essential for spermatogenesis
Genes Dev, 2005. 19(20): p. 2501-15.