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Rottier, Robbert

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Robbert Rottier started the research for his PhD thesis on the molecular basis of the lysosomal storage disorder galactosialidosis in the department of Cell Biology and Genetics of the Erasmus University Rotterdam (Prof. dr. H. Galjaard and Dr. A. d'Azzo), and continued at the department of Genetics of St. Jude Children's Research Hospital, Memphis, TN, USA (Dr. A. d'Azzo, 1993-1996). He stayed on as a research specialist at St. Jude Children's Research Hospital (1997), after which he moved back to the department of Cell Biology and Genetics to work as a postdoctoral fellow in the group of Prof. dr. F.G. Grosveld and Dr. S. Philipsen to study the role of Gata-2 in hematopoiesis.

Since 2001 he is a senior researcher in the Department of Pediatric Surgery where he is interested in the molecular basis of lung development.


Rottier group page


Key publications 


Parera MC, van Dooren M, van Kempen M, de Krijger R, Grosveld F, Tibboel D, Rottier R (2004)
Distal angiogenesis: a new concept for lung vascular morphogenesis
Am J Physiol Lung Cell Mol Physiol. 288(1):L141-9

Masumoto K, de Rooij JD, Suita S, Rottier R, Tibboel D, de Krijger RR (2005)
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases during normal human pulmonary development
Histopathology 47(4):410-9

Rajatapiti P, Keijzer R, Blommaart PE, Lamers WH, DE Krijger RR, Visser TJ, Tibboel D, Rottier R (2006)
Spatial and temporal expression of glucocorticoid, retinoid, and thyroid hormone receptors is not altered in lungs of congenital diaphragmatic hernia
Pediatr Res 60(6):693-8

Rajatapiti P, van der Horst IW, de Rooij JD, Tran MG, Maxwell PH, Tibboel D, Rottier R, de Krijger RR (2007)
Expression of hypoxia-inducible factors in normal human lung development
Pediatr Dev Pathol 11(3):193-9

Gontan C, de Munck A, Vermeij M, Grosveld F, Tibboel D, Rottier R (2008)
Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation
Dev Biol 317(1):296-309