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Ultrasound scan
Research project

Theranostic-phospholipid-coated-ultrasound-contrast-agents

Status: Ongoing

This project is developing novel phospolipid-coated microbubbles, i.e. ultrasound contrast agents, for ultrasound molecular imaging and drug delivery.

What we do

About our project

What is the motivation for this research?

Ultrasound contrast agents are comprised of phospholipid-coated gas microbubbles, 1-10 μm in size, that vibrate (expand and compress) in response to ultrasound. However, the vibration of current microbubbles is unpredictable and thus a huge problem for the new theranostic applications of microbubbles: ultrasound molecular imaging and drug delivery.

What is the aim?

The aim of the project is to produce and characterize a novel theranostic ultrasound contrast agent consisting of phospholipid-coated microbubbles of which the response to ultrasound is predictable and thus on demand.

How will you perform this research?

To achieve the novel theranostic microbubbles, microbubbles will be produced and characterized physico-chemically and acoustically.

What is the desirable outcome?

The results of this project could potentially result in more effective ultrasound molecular imaging and drug delivery through the development of microbubbles that will respond predictable and on demand to ultrasound.

Funds & Grants

Phospholipid Research Center, Heidelberg, Germany

Collaborations

Collaborations within Erasmus MC

Pathology

Collaborations outside Erasmus MC

Physical Chemistry, Martin Luther University Halle-Wittenberg, Blume lab

Publications

Our team

Any questions or comments?

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