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Researcher

E. (Enrique) Andres Sastre

PhD candidate

  • Department
  • Oral and Maxillofacial surgery
Contact   External Profile

About

Introduction

The main goal of my research is to identify novel extracellular matrix molecules to improve the design of the biomaterials that are being currently used for the treatment of skeletal diseases, such as bone defects and osteoarthritis. Specifically, I am focused on the role that certain extracellular matrix proteins and their fragments play in endochondral ossification. I am interested in their ability to promote or inhibit vascularisation, mineralisation and to determine cell fate in the formation of cartilage or bone. Once novel bioactive factors are identified, I expect to further test them in vivo to report whether they could be further tested on clinical trials for the treatment of skeletal diseases.

Field(s) of expertise

Regenerative medicine and tissue engineering; Bone and cartilage biology; Stem cells

Education and career

2010-2014  BSc Biotechnology;

2010-2014  Liberal Studies;

2014-2016  MSc Regenerative Biology and Medicine;

2017-present  PhD Biomedical research

Publications

Teaching activities

Supervision of MSc students

Current research project

My Groups