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Researcher

N.S. (Nicole) Erler, PhD

Postdoctoral researcher

  • Department
  • Biostatistics
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About

Introduction

I am a postdoctoral researcher at the Department of Biostatistics at the Erasmus Medical Center in Rotterdam. My research focus is on Bayesian methods for incomplete data, specifically for settings with missing covariates.

Since 2017, I support the Department of Gastroenterology & Hepatology in the planning and analysis of clinical trials and observational studies.

Field(s) of expertise

  • Missing Data
  • Imputation 
  • Bayesian methodology 
  • Multi-level data

Education and career

  • 2019: Ph.D. in Biostatistics (Erasmus Medical Center, Rotterdam, the Netherlands)
  • 2014: Doctor of Science in Epidemiology (Netherlands Institute of Health Sciences, Rotterdam, the Netherlands)
  • 2012: Diplom Statistics (Ludwig-Maximilians Universität München, Munich, Germany)

Publications

For my publications, please see link

Recent Findings 

Previous studies in the lab have shown that autologous dendritic cells pulsed with allogenic tumor cell lysate was able to induce peripheral T cell activation and tumor-reactive T cell responses in patients with mesothelioma and pancreatic cancer. Current research focuses on how to initiate an effective immune response in the tumor as well as the tumor-draining lymph node using dendritic cell vaccination. Furthermore, we are studying novel approaches for (personalized) vaccination. In addition, we have identified T cell characteristics that underlie clinical efficacy of immune check inhibitors or chemotherapeutic agents in mesothelioma. The selected publications below give an impression of our work. 

Teaching activities

For my teaching activities, please see link

My Groups