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Mojca Jongen-Lavrencic

MicroRNA expression and function in AML

Jongen-Lavrencic lab

 

We aim to identify microRNAs that have a function in pathogenesis of AML and may be used to improve diagnostics, prognostics and potentially therapy of heterogeneous AML.

Our approach to identify candidate microRNAs is based on microRNA expression profiling (Q-RT-PCR) of large number of AML samples as well as cell subsets of normal human differentiation (in vitro and in vivo models).