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Medication prescription using DNA profile

Erasmus MC has set up a Pharmacogenetics outpatient clinic for patients who are starting with psychiatric medication.

DNA profile
The dosage is determined in this clinic based on the patients' DNA profile, making personalized medication possible. As yet, the clinic is a pilot service that will run until the end of 2017. Patients can be referred to the clinic until mid-December 2017 using the online referral form.

Drugs given to psychiatric patients often cause side effects or prove to be ineffective. It is frequently a challenge to provide the right treatment to the right patient, at the right dose. The genetic predisposition of patients can play a role in the uptake and metabolism of medicines.

Five to 10 percent of the people, for example, have an enzyme problem in the liver resulting in more side effects or reduced efficacy of the drugs compared to other people. DNA profiling increases the certainty about the efficacy of the medicines beforehand.

More effective
Erasmus MC is the first with such a specialist outpatient clinic. The clinic fits in with Erasmus MC's efforts to provide Personalized Medicine: more effective care with fewer side effects, in other words, safer treatment.

The Pharmacogenetics outpatient clinic is an initiative of the departments of Clinical Chemistry (Prof. Yolanda de Rijke and Prof. Ron van Schaik) and Psychiatry (Prof. Witte Hoogendijk) and will be run by Dr. Roos van Westrhenen, psychiatrist and clinical pharmacologist.

Farmagenetica profiel op kaartje

Date published: 29 September 2017.

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