target menu
... / ... / Research Projects / Excellent Science
 

Excellent Science

Read more about the research talent at Erasmus MC.

Dr. Rebekka Schneider – Bone Marrow Fibrosis

ERC Starting Grant- 2017

Bone marrow (BM) fibrosis is the continuous replacement of blood forming cells in the bone marrow by scar tissue, ultimately leading to failure of the body to produce blood cells. Primary myelofibrosis (PMF), an incurable blood cancer, is the prototypic example of the step-wise development of BM fibrosis. The specific mechanisms that cause BM fibrosis are not understood , in particular as the cells driving fibrosis have remained obscure. Dr. Schneider aims to unravel these mechansims in her research.

 

 

Five Veni grants for Erasmus MC Researchers!

NWO - Veni 2017

Dr. Tianshi Wang - New imaging technique sees the heart attack before it happens
Most heart attacks and strokes are caused by the rupture of lipid-core atherosclerotic plaques in the artery wall. Seeing the heart attack before it happens may potentially save millions of lives. Dr. Wang is developing a new technique named thermo-elastic deformation imaging, targeting early detection of the lipid-core plaques.

Dr. Henk-Jan Boele - New brain connections
Our brain, and in broader terms our nervous system, has an enormous adaptability (neuroplasticity). For this Veni-proposal, I want to investigate the biological processes of this brain adaptability. The gained knowledge about these processes is severely needed for the treatment of brain diseases as a result of degeneration or injury.

Dr. Karen Stegers-Jager - Fatal first impressions?
Within a split second assessors form a first impression of a trainee. How does this first impression influence the final rating? Is this the reason for poorer ratings for ethnic minority trainees? Unravelling this judgment process is essential for fair assessments for all students in our multicultural society.

Dr. Miao-Ping Chien - Identification, Isolation and Analysis of Single Cancer Stem Cells
To understand the molecular mechanisms driving oncogenesis it is imperative to study individual cells. I will create and use optical and chemical methods for the identification, isolation and analysis of single cancer stem cells, and investigate their role in the formation, progression and therapeutic resistance of tumors.

Dr. Patrick Forbes - Unravelling the brain’s internal sensory and motor models of standing
How is balance maintained automatically? Our brain uses internal sensory and motor models to control posture. Using novel robotics, these models will be uncoupled by modifying properties of our sensors, body mechanics and environment. This research will reveal causal relationships between the neural computations and compensatory responses required to stand.

 

Dr. Natasja de Groot - Atrial Fibrillation
NWO - Vidi 2017 

Dr. Natasja de Groot, cardiac electrophysiologist at the Thorax Center, hopes to tailor the treatment for atrial fibrillation more to the individual patient. All patients currently receive the same treatment, regardless of the phase the disease is in. By applying a dedicated electrical stimulation technique she aims to identify electrical biomarkers that can be used to individualise diagnosis and therapy of atrial fibrillation.

 

Prof. dr. Robin Peeters - Hypothyroid Mothers
NWO - Vidi 2017 

Robin Peeters, endocrinologist and Professor of Internal Medicine, will to use the grant to improve the treatment of hypothyroid mothers (and the brain development of their children). Low maternal thyroid hormone levels during pregnancy result in a decreased child IQ, autism, ADHD and schizophrenia. Through this study he aims to develop a method to monitor fetal thyroid status via measurements in maternal serum. Click here for an interview with prof. Peeters about his research.

 

 

 

Dr. Judith Rietjens - Self Management
NWO - Vidi 2017 

The grant will enable Dr. Judith Rietjens of the department of Public Health to examine patients with advanced cancer and determine how they can take a significant role in managing their healthcare. Many patients and their family caregivers are ill-prepared for this complex task. The researchers will examine which patients have more difficulties with self-management, why this is the case, and how they can best be supported.

Prof. dr. Jan Hoeijmakers - Molecular Genetics
ERC Advanced Grant 2017

Erasmus MC congratulates prof. dr. Jan Hoeijmakers on being awarded the ERC Advanced Grant for the second time in his career. He and his research group will will focus on the cross-talk between DNA damage,  ageing and dietary restriction. The emphasis of this research will be on on the relevance for normal aging, and could also impact  prevention and treatments for ageing-related illnesses, such as dementia.  

 

 

 

 

 

Prof. dr. Henning Tiemeier - Epidemiology/Psychiatry
NWO Talent Scheme - Vici

Henning Tiemeier, Professor in Psychiatric Epidemiology, has been awarded the prestigious Vici grant from NWO. For the next years, he and his team will research the effect of negative childhood experiences on the brain development. Over 4000 children participate in this study, in which data will be available from early childhood to adolescence. Prof. Tiemeier has been leading psychiatric epidemiology research in Rotterdam for the last fifteen years. This line evolved around two large population-based cohorts, the Rotterdam Study and Generation R. His research is mostly aimed at understanding risk factors for common psychiatric disorders and characterised by his interest in detailed phenotype assessment, neuroimaging, and genetics, combined with modern quantitative methods.

 

 

Dr. Martijn Schonewille - Neurosciences
ERC Starting Grant


The perfect execution of a voluntary movement requires the appropriate integration of current bodily state, sensory input and desired outcome. To assure that this motor output becomes and remains appropriate, the brain needs to learn from the result of previous outputs. The cerebellum plays a central role in sensorimotor integration, yet -despite decades of studies- there is no generally excepted theory for cerebellar functioning. Martijn aims to identify the ontogeny of anatomical and physiological differences between modules, and their functional consequences.

 


 

 

For more talent at Erasmus MC, click here