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PhD student

Vacaturenummer:

38.17.17.TD

Afdeling:

Orthopaedie

Categorie:

Wetenschap en O&O

Aantal uur:

36 uur per week

Plaatsingsdatum:

4 oktober 2017

Sluitingsdatum:

1 november 2017

Functie-inhoud

The research project contributes to one of the pillars of our department; cartilage regeneration. When cartilage is damaged, it will not heal spontaneously. Many attempts are made to foster the regeneration, and one involves stimulating the endogenous stem cells in the joint to migrate to the defect and differentiate into cartilage forming cells. Cartilage damage is however often combined with inflammation in the joint, which negatively impacts the regeneration process. In this project, we aim to improve cartilage regeneration by combining the right scaffold as template for the newly forming cartilage with factors that promote the attraction of stem cells and dampen inflammation.

The interaction between macrophages and progenitor cells will be extensively examined in the context of cartilage regeneration using in vitro models to be analysed with fluorescense microscopy, confocal microscopy, ELISA, and gene expression. Eventually, we will test the most promising conditions in in vivo models.

Werkomgeving

A healthy population and excellence in healthcare through research and education. This is what Erasmus MC stands for. Conducting groundbreaking work, pushing boundaries and leading the way. In research, education, and healthcare. We are practical people with a high level of expertise, working hard to improve and renew the healthcare of today and the public health of tomorrow.

As a PhD-student you will work at the Department of Orthopaedics within the Connective Tissue, Cells and Repair group (head of the group: Prof. dr. Gerjo van Osch), which hosts approximately 20 researchers in a multidisciplinary environment.

Profiel

We seek an enthusiastic and dedicated candidate with a completed MSc degree in Medicine, Biomedical Sciences, Biomedical Technology, or Medical Biology. The candidate has experience with cell/tissue culture and must have affinity with animal experiments.

Being able to present a certificate of good conduct is a condition for the appointment

Wat bieden wij

You will receive a temporary position for 3 years. The gross monthly salary based on a fulltime workweek of 36 hours is € 2.279 ,- in the 1st year and increases to € 2.919,- in the 3th year (scale OIO). The salary for candidates in the possession of a Medical degree amounts to a maximum of € 4.194,- (scale 10), based on a 36 hours workweek. The terms of employment are according to the Collective Bargaining Agreement for Dutch University Medical Centers (CAO UMC)

Inlichtingen en solliciteren

For more information about this position, please contact dr. Yvonne Bastiaansen-Jenniskens, Assistant Professor, phone number: (+31) (0)10 704 4626 or e-mail: y.bastiaansen@erasmusmc.nl. For other information please contact Lonneke Vos, HR Advisor, phone number: (+31)(0)10 703 3370. 

Please respond by using the apply button.

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