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Researcher

R.J.E.M. (Radboud) Dolhain, MD PhD

Principal investigator

  • Department
  • Rheumatology

About

Introduction

My main line of research concerns Reproductive Rheumatology i.e. the impact of disease activity and medication on fertility and pregnancy outcome in women and men with rheumatic diseases. In addition the impact of pregnancy on disease activity is studied. Also follow-up studies of children born to women with rheumatic diseases are undertaken. This research line incorporates both clinical epidemiological as well as translational studies. 

Field(s) of expertise

Reproductive Rheumatology, Translational research

Education and career

1983-1988 : Utrecht University, Medical Bachelor
1991 : Utrecht University, Medical Doctor
1991-1996 : PhD, department of Rheumatology, Leiden University
1998 : thesis “T cells in the inflamed joints of patients with Rheumatoid Arthritis”
1996-2001 : Leiden University Medical Center, trainee in Rheumatology
2001 : board certified as rheumatologist
2001-present : rheumatologist, Erasmus MC
2013 : appointed as an associate professor of Rheumatology
2019 november- present : head of the department of Rheumatology Erasmus MC

Publications

• de Man YA, Dolhain RJ, van de Geijn FE, Willemsen SP, Hazes JM. Disease activity of rheumatoid arthritis during pregnancy: results from a nationwide prospective study. Arthritis Rheum 2008; 59:1241-8. 
• de Man YA, Hazes JM, van der Heide H, Willemsen SP, de Groot CJ, Steegers EA, Dolhain RJ. Association of higher rheumatoid arthritis disease activity during pregnancy with lower birth weight: results of a national prospective study. Arthritis Rheum 2009; 60:3196-206. 
• Brouwer J, Hazes JM, Laven JS, Dolhain RJ. Fertility in women with rheumatoid arthritis: influence of disease activity and medication. Ann Rheum Dis. 2015 Oct; 74(10):1836-1841.
• Bondt A, Hafkenscheid L, Falck D, Kuijper TM, Rombouts Y, Hazes JMW, Wuhrer M, Dolhain R.  ACPA IgG galactosylation associates with disease activity in pregnant patients with rheumatoid arthritis. Ann Rheum Dis. 2018 Aug; 77(8):1130-1136
• Smeele HTW, Röder E, Wintjens HM, Kranenburg-van Koppen LJC, Hazes JMW, Dolhain RJEM. Modern treatment approach results in low disease activity in 90% of pregnant rheumatoid arthritis patients: the PreCARA study.  https://doi.org/10.1136/annrheumdis-2020-219547(2021)

Other publications Radboud Dolhain

Teaching activities

Lectures for medical students in the core curriculum and minor
Lectures in several postgraduate courses on Reproductive Rheumatology
Supervisor for trainees in Rheumatology