Integrating multi-omics data from population-based studies and conducting experimental validation studies, we aim to elucidate molecular pathways underlying age-related diseases and identify potential biomarkers for their early diagnosis.
We aim to address research questions with clinical relevance for patients and general practitioners in primary care. Our research is mainly focused on (I) musculoskeletal disorders and (II) diseases in children in general practice.
This multidisciplinary project is performed by a team of engineers and clinicians from the Departments of Biomedical Engineering, Cardiology, Pediatric Cardiology and Radiology.
We tissue engineer human disease models for atherosclerosis to unravel the process of atherosclerotic plaque rupture and to identify new imaging biomarkers.
We develop new diagnostic imaging, aimed at targeting inflammation and calcification with radionuclide imaging, to assess atherosclerotic plaque composition.
