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profile picture Bahar Sedaghatikhayat

B. (Bahar) Sedaghatikhayat

PhD student

  • Department
  • Internal Medicine, Genetic Laboratory



The title of my PhD research is: Polygenic risk score and its performance in clinical aspects.


Recent Findings 

Previous studies in the lab have shown that autologous dendritic cells pulsed with allogenic tumor cell lysate was able to induce peripheral T cell activation and tumor-reactive T cell responses in patients with mesothelioma and pancreatic cancer. Current research focuses on how to initiate an effective immune response in the tumor as well as the tumor-draining lymph node using dendritic cell vaccination. Furthermore, we are studying novel approaches for (personalized) vaccination. In addition, we have identified T cell characteristics that underlie clinical efficacy of immune check inhibitors or chemotherapeutic agents in mesothelioma. The selected publications below give an impression of our work. 

My Groups