About K. (Katerina) Trajanoska, MD, PhD
Introduction
I have a medical background and substantial experience in genetics and translational research. I was trained as a nurse and as a medical doctor in Macedonia and specialized in Genetic Epidemiology at the Erasmus Medical Center.
My PhD was focused on musculoskeletal genomics identifying causal risk factors for musculoskeletal diseases with an emphasis on utilizing polygenic risk scores to predict disease susceptibility and employing Mendelian Randomization for causal inference analysis.
Currently I am working as assistant professor at the Translation Skeletal Genomics group with an end goal to help answer translational questions regarding the utility of using genomics data and performing genomics-assisted medical decision-making.
Education and career
Publications
Partitioning knee osteoarthritis genetic variants based on BMI association to improve polygenic risk prediction. Sedaghati-Khayat B, Trajanoska K et al. Osteoarthritis Cartilage. doi: 10.1016/j.joca.2025.09.018.
Genetically Predicted Iron Status and Cardiovascular Function and Structure: A Mendelian Randomization Study. Quezada-Pinedo HG et al. Eur J Prev Cardiol. doi: 10.1093/eurjpc/zwaf498.
Cardiovascular Pharmacogenetics: From Discovery of Genetic Association to Clinical Adoption of Derived Test. Delabays B, Trajanoska K, Walonoski J, Mooser V. Pharmacol Rev. doi: 10.1124/pharmrev.123.000750.
From target discovery to clinical drug development with human genetics. Trajanoska K, Bhérer C, Taliun D, Zhou S, Richards JB, Mooser V. Nature. doi: 10.1038/s41586-023-06388-8.
Are some children genetically predisposed to poor sleep? A polygenic risk study in the general population. Kocevska D, Trajanoska K et al. J Child Psychol Psychiatry. doi: 10.1111/jcpp.13899.
A cost-effective sequencing method for genetic studies combining high-depth whole exome and low-depth whole genome. Bhérer C, Eveleigh R, Trajanoska K. et al NPJ Genom Med. 2024 Feb 7;9(1):8. doi: 10.1038/s41525-024-00390-3.
List of full publication list can be found on the following link: https://pubmed.ncbi.nlm.nih.gov/?term=katerina%20trajanoska&sort=date
Teaching activities
Course Coordinator at Netherlands Institute for Health Sciences (NIHES):
- Mendelian Randomization (2020 to present)
Lecturer at Netherlands Institute for Health Sciences (NIHES):
- Introduction to genome wide association studies -Advanced genome wide association studies
