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Research project  |  Pediatric Intestinal failure Cognitive and Social emotional Outcomes

PICASsO study

Status: Closed project

We address three questions: How are children with intestinal failure dependent on parenteral nutrition? How are their parents coping? How can we help them?

What we do

About our project


Parenteral nutrition treatment provided by multidisciplinary teams has tremendously improved survival rates of children with intestinal failure and decreased the complication rates. Therefore, new challenges become apparent, concerning the survivors’ cognitive development, social-emotional aspects and parent-child relationship.   

Aims of the study

The aims of this study are to assess parent-child attachment and interaction in a cohort of children known with intestinal failure and (a history of) home parenteral nutrition dependence, and to assess these children’s cognitive development and social-emotional functioning.

Research method 

With the use of age-specific psychological questionnaires, interviews and observations we will assess aspects of parent-child attachment and interaction, cognitive development, and social-emotional functioning.  

Desirable outcome

We wish to inventory how children with intestinal failure and how their parents are doing psychologically. We want to find out how to implement early interventions and how to offer guidance to the parents and children, so as to prevent cognitive and psychosocial problems later in life.

Funds & Grants

Our team

  • Merel Verloop, MSc, psychologist 
  • Lotte Vlug, MD, PhD student
  • Jeroen Legerstee, MSc, PhD, psychologist, post-doc researcher
  • Barbara de Koning, MD, PhD, pediatric gastroenterologist 
  • René Wijnen, MD, PhD, pediatric surgeon, head of department of Pediatric Surgery 
  • Edmond Rings, MD, PhD, pediatric gastroenterologist, head of department of Pediatrics 
  • The Intestinal Failure team

Any questions?

Please contact our office if you have any questions or comments.

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