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Research projects (40)

3D geometric models of paediatric cardiac shape

We use 3D geometric models to assess how cardiovascular risk factors affect the ‘normal’ shape of the child’s heart. This might aid in risk ...

CAM Study

Assessment of central airways mechanics using Magnetic Resonance Imaging (MRI) and bronchoscopy: a comparison.

Child Brain Lab

The Child Brain Lab is a testing facility for brain development and brain function of children with neurological or psychiatric disorders or ...

Childhood stuttering and structural brain morphology

The Generation R Study is an ongoing population-based prospective birth cohort investigating children’s development from fetal life onwards (n=9901).

CHIP-Family for young children with congenital heart disease

We are researching the effect of the multidisciplinary, psychosocial CHIP-Family intervention on wellbeing of young children with congenital heart ...

Congenital Melanocytic Nevi

Living with a (large) congenital melanocytic nevus (CMN) might imply a psychosocial burden both for the child and parents and may carry a higher risk ...

Effects and health economic aspects of enzyme therapy with Pompe disease

Our aim is to investigate the long-term effects of enzyme-replacement therapy in children and adults with Pompe disease, and to define predictive ...

Emergency Department - PEWS: a new early warning score for the ED

The Paediatric Early Warning Score (PEWS) is a simple score, combining several physiological parameters, that can improve the prioritization of ...

Fragile X syndrome

Fragile X syndrome is the leading monogenic cause of intellectual disability and autism.

Genetic causes of Disorders of Sex Development

Many genes may underlie disorders of sex development (DSD). A genetic cause is not yet known for the larger part of patients with a 46,XY DSD.


Reducing symptoms of depression and anxiety in young patients with inflammatory bowel disease (IBD) in order to improve quality of life and the ...

Immune responses in neurodegenerative diseases: Protection or progression?

We investigate brain immune cells (microglia) in zebrafish genetic models to gain insight in the roles of these cells in human brain diseases.