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Core Facility

Generation R

Generation R is a multi-ethnic prospective cohort study from fetal life until young adulthood in Rotterdam, The Netherlands.

Services

Showcases

Press and Media Reports

Since the launch of Generation R, the study has already yielded many important results. Click here to view a selection of Research Results  and here to view all Press and Media Reports of Generation R.


Support

In case of questions or comments about Generation R (Next) please call 010-704 34 05 or send us an e-mail. You can also complete our contact form.

Training, Education and Documentation

Documentation

Brochures

Generation R – Focus at 17 (available soon)
https://generationr.nl/focus-op-13/download-de-folders/
 

News, Events, and Publications

News

Click here for an overview of Generation R (Next) News Articles and here to sign up for the newsletter. Stay up to date with the latest news and results regarding Generation R (Next) via the website, Facebook, Next Facebook, Instagram, Next Instagram, LinkedIn and Twitter.

Events

Publications and theses

Publications

Generation R publications can be found on PubMed.

Theses

All Generation R researchers and staff have access to the Generation R WIKI intranet where all Generation R Theses can be found.

About us

Introduction

The Core Facility Generation R runs 2 population-based cohorts studies: Generation R and Generation R Next.

Generation R

Generation R is a prospective cohort study from early fetal life until young adulthood in a multi-ethnic urban population, among 10,000 mothers, fathers and their children. The study is designed to identify early environmental and genetic causes of growth, development and health. Detailed research data is collected with the latest methods and techniques. Results forthcoming from the Generation R Study contribute to the development of strategies for optimizing health and healthcare for all children and their parents.

Generation R Next

In spring 2017 Generation R launched a new cohort study: Generation R Next, studying the growth and development of a new generation of children from preconception onwards from Rotterdam. Generation R Next investigates the health and lifestyle of parents preferably before pregnancy and the effects on their growing and developing child. Participants with a child wish or pregnant women are invited for 3D Ultrasounds and detailed measurements. Click here to to register for Generation R Next or watch our video:

Our team

Management team

Prof. dr. Vincent W. V. Jaddoe, Head
Drs. Koos Lubbe, Theme Director
Dr. Liesbeth Duijts
Dr. Janine Felix
Dr. Romy Gaillard
Prof. dr. Manon Hillegers
Prof. dr. Marinus van IJzendoorn
Dr. Pauline Jansen
Dr. Wilma Jansen
Prof. dr. Johan de Jongste
Prof. dr. Caroline Klaver
Prof. dr. Frank van Lenthe
Prof. dr. Henriëtte Moll
Prof. dr. Robin Peeters
Prof. dr. Hein Raat
Prof. dr. Irwin Reiss
Dr. Bas van Rijn
Dr. Fernando Rivadeneira
Dr. Marc van der Schroeff
Prof. dr. Eric Steegers
Prof. dr. André Uitterlinden
Prof. dr. Meike Vernooij
Dr. Trudy Voortman
Prof. dr. Eppo Wolvius

Researchers from several research groups cooperate within Generation R. The Management Team reviews all research projects at implementation and content level, and is responsible for the planning and execution of the study. Secretarial, administrative and logistic work is executed by office staff, and measurements at the research center by research staff. Research is conducted by Postdocs and approximately 100 PhD students, who study at the Netherlands Institute for Health Sciences (NIHES). From this perspective, Generation R trains a new generation of researchers for future youth health.

Our expertise

The CoFa Generation R runs 2 large scale cohort studies from the earliest phase of life. There is an enormous wealth of sociodemographic, life style, nutrition, biological and detailed outcome data. Outcome data include data on asthma and allergies, attachment, behavior, body composition, bone health, cardiovascular risk factors, cognition, developmental disorders, eye development, growth, hearing disorders, myopia, psychopathology and tooth health. Also, there is an extensive biobank available with genome and epigenome wide data, microbiome data and metabolomics data available.

Our activities

Studies are performed on the prevalence, incidence and etiology of common diseases in pregnancy and childhood. Specific interest in the the early origins of diseases across the lifecourse.

Results forthcoming from the Generation R Study contribute to the development of strategies for optimizing health and healthcare for all children and their parents.

Collaboration

Generation R is conducted by more than 15 research groups from Erasmus MC, Erasmus University Rotterdam, and the municipality of Rotterdam (Gemeente Rotterdam). Hospitals, obstetricians, Child Health Clinics (CJG), general practitioners, pharmacists and laboratories in Rotterdam, as well as national institutions such as the Dutch Center for Youth and Health (NCJ), are also involved. Partnerships for various research projects have also been established with studies abroad, the number of partnerships is expected to increase in the upcoming years.

Requests for collaboration

The study has an open policy in regard to collaboration with other research groups. Requests for collaboration should primarily be pointed to Prof.dr. Vincent Jaddoe. These requests are discussed in the Generation R Study Management Team regarding their study aims, overlap with ongoing studies, logistic consequences and financial contributions. After approval of the project by the Generation R Study Management Team and the Medical Ethical Committee of the Erasmus Medical Center, the collaborative research project is embedded in one of the five research areas supervised by the specific principal investigator.

Pregnancy & Child Center (Centrum voor Zwangerschap & Kind)

The conditions before and during pregnancy, and during the first years of life are extremely important for later health and development. Lifestyle and environmental factors of future parents are crucial for the health and social-emotional development of their offspring. To improve the health and wellbeing of future parents and their children, the Pregnancy & Child Center (Centrum voor Zwangerschap en Kind) has been established. In this center, doctors and researchers from various disciplines at Erasmus MC, Erasmus MC – Sophia Children’s Hospital and the municipality of Rotterdam collaborate identifying factors and mechanisms in the earliest stages of life affecting later health. The center focuses on 3 tasks: patient care, education and research.

EU Horizon 2020 LifeCycle Project

Various Generation R researchers participate in the Horizon 2020 LifeCycle Project. This consortium congregates birth and child cohorts from Europe in an extensive EU Child Cohort Network. Data from over 250,000 parents and their children converge in this network. Stay informed of all LifeCycle news via the website where you can also find the new LifeCycle videoclip and an overview of all participating partners.


Career opportunities

Funding

Any questions?

Please contact our office if you have any questions or comments.

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