About our research group/lab
Our research
The research is focused on understanding molecular immunological mechanisms driving arthritis.
The lab focuses on the role and modulation of lymphocytes in the development of chronic inflammatory autoimmune-mediated diseases with focus on the IL-23/Th17 immune pathway and the role of T cell cytokines, receptors, signaling pathways in the development of chronic inflammatory autoimmune-mediated diseases.
To gain insight into these processes, we use material from cohorts and trials conducted in the department of Rheumatology.
Our projects
Key Publications
Human Memory Th17 Cell Populations Change Into Anti-inflammatory Cells With Regulatory Capacity Upon Exposure to Active Vitamin D
Dankers W et al Front. Immunol 2019 Jul 17;10:1504
The IL-23–IL-17 axis in inflammatory arthritis
Erik Lubberts. Nature reviews Rheumatology 2015; 11, pages415–429 (2015)
Vitamin D in Autoimmunity: Molecular Mechanisms and Therapeutic Potential
Dankers W et al. Front. Immunol 2017, Jan 20;7:697
How to Prepare Spectral Flow Cytometry Datasets for High Dimensional Data Analysis: A Practical Workflow
Hannah den Braanker, Margot Bongenaar and Erik Lubberts. Front. Immunol.; 19 November 2021
Funding & Grants
coming later
Our team
Anne-Marie Mus
Nadine Davelaar
Eddy Florencia
Yi He
Sara Parsa
Bennie van Heeswijk
