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Research project

Validation of reprocessing efficacy of a duodenoscope (REDUCE)

Status: Ongoing project, start date: 2018, end date: 2020

Duodenoscopes are difficult to clean, leading to persistent contamination after reprocessing. Improvement of this is studied in a novel designed duodenoscope.

What we do

About our project

Recent studies describe multiple outbreaks of Multi-Drug Resistant Organisms (MDRO) related to the use of duodenoscopes. Duodenoscopes are more difficult to clean in contrast to other flexible endoscopes due to their complex design, Furthermore, flexible endoscopes are heat sensitive and can therefore not be thermally sterilized. 

A new duodenoscope model has been developed that addresses the part of the duodenoscope that is prone for persistent contamination after reprocessing: the distal tip with the forceps elevator. The duodenoscope has a disposable cap which includes the forceps elevator. After each procedure the contaminated cap with forceps elevator is removed from the duodenoscope. This actions removes an important source of contamination and enables all sides and crevices of the side viewing tip to be reached by cleaning brushes. This will be a single center prospective observational in vitro study.


Our research focus

Primary objective
To assess  if a duodenoscope with an innovative design that has a single-use, disposable distal cab with integrated elevator inoculated with artificial test soil, has a lower contamination rate, defined as presence of gastrointestinal or oral flora after High Level Disinfection, when compared to other marketed duodenoscope models that do not feature a disposable cap with integrated elevator.

Funds & Grants



Dept of Gastroenterology and Hepatology

Our team

Prof Dr Margreet Vos

Porf Dr Marco Bruno

Drs J.kwakman