What we do
About our project
The CAPP department at Erasmus MC is responsible for Research Theme 3, which investigates the role of daily-life stress responses in the onset and progression of mental and cardiometabolic health conditions. This is achieved by linking prolonged, comprehensive assessments of stress responses to health outcomes on an unprecedented scale.
We consider the entire health continuum, encompassing both positive outcomes (e.g. well-being, normotension) and negative outcomes (e.g. depression, anxiety, hypertension). In addition to a major scale-up in data collection, we go beyond the conventional focus on the amplitude of stress responses by also examining their frequency, duration, and recovery patterns over both the short term (days/weeks) and long term (months/years).
We incorporate analyses of moderating factors, such as personal vulnerability and resilience characteristics (e.g. early-life stressors, socioeconomic status, and genome-wide genetic vulnerability), and investigate mediating mechanisms through integrated multi-omics analyses.
Finally, we will provide proof-of-concept evidence to demonstrate the extent to which various interventions targeting daily-life stress can positively influence health outcomes - and vice versa.
Fore more information about the research lab, pleas visit the website: www.stress-in-action.nl.
Our team
Erasmus University Medical Center Rotterdam (EMC) - SiA consortium members (van Rossum, Boersma, Manon Hillegers, Kavousi, Rizopoulos) are from various EMC departments: Internal Medicine/Endocrinology, Cardiology, Child and Adolescence Psychiatry, Epidemiology, and Biostatistics.
