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Photo Fabien Filaire
Researcher

Dr. F.F. (Fabien) Filaire

Postdoctoral Researcher

  • Department
  • Virology
  • Focus area
  • Airborne transmission, zoonosis infection, influenza virus evolution, virulence and pathogenesis.
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About Dr. F.F. (Fabien) Filaire

Introduction

After obtained an engineering degree in France in Biosciences, I completed a PhD in virology focused on the development of novel strategies for the early detection of highly pathogenic avian influenza viruses in poultry.

Then, I joined Prof. Herfst’s team in the Department of Viroscience as a postdoctoral researcher. My research focuses on viral and host factors involved in the airborne transmission of influenza A viruses, as well as cross-species transmission.

Education and career

  • 2013-2020: National Institute of Applied Science (INSA) Lyon, France, Biosciences Engineer

  • 2020-2023: PhD student, Theseo France, Laval, France- Mixed Research Unit 1225 IHAP (Host-Pathogen Interaction) from the National Veterinary School of Toulouse (ENVT) and INRAe – The Engineering School of Toulouse, Platform TOAsT – PhD entitled: ‘Development of innovative field deployable and non-invasive strategies for early detection of high pathogenicity avian influenza viruses’.

  • 2024- ongoing: Postdoctoral Researcher, Prof. Herfst group, Viroscience Department.

Publications

  • Influenza A(H5N1) shedding in air corresponds to transmissibility in mammals. Nat Microbiol 10, 14–19 (2025). Tosheva, I.I., Filaire, F., Rijnink, W.F. et al. https://doi.org/10.1038/s41564-024-01885-6

  • The highly pathogenic H5N1 virus found in U.S. dairy cattle has some characteristics that could enhance infection and transmission among mammals. Lab Anim. (2024). Filaire, F., Herfst, S. https://doi.org/10.1038/s41684-024-01425-z

  • Viral shedding and environmental dispersion of two clade 2.3.4.4b H5 high pathogenicity avian influenza viruses in experimentally-infected mule ducks: implications for environmental sampling. Veterinary Research. (2024). Filaire, F.*, Bertan, K.*, Gaide, N., et al. https://doi.org/10.1186/s13567-024-01357-z

  • High and low pathogenicity avian influenza virus discrimination and prediction based on volatile organic compounds signature by SIFT-MS: a proof-of-concept study. Scientific reports 14, 17051. (2024). Filaire, F., Sécula, A., Bessière, P., et al. https://doi.org/10.1038/s41598-024-67219-y

  • Optimizing environmental viral surveillance: bovine serum albumin increases RT-qPCR sensitivity for high pathogenicity avian influenza H5Nx virus detection from dust samples. Microbiology Spectrum, 11(6), 1–9. (2023). Bessière, P., Hayes, B., Filaire, F., et al. https://doi.org/10.1128/spectrum.03055-23

  • A real-time colourimetric reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for the rapid detection of highly pathogenic H5 clade 2.3.4.4b avian influenza viruses. Avian Pathology, 53(2), 93–100. (2024). Filaire, F., Sécula, A., Lebre, L., et al. https://doi.org/10.1080/03079457.2023.2276849

  • The feather epithelium contributes to the dissemination and ecology of clade 2.3.4.4b H5 high pathogenicity avian influenza viruses in ducks. Emerging Microbes and Infections, 12(2). (2023). Gaide, N.*, Filaire, F.*, Bertan, K., et al. https://doi.org/10.1080/22221751.2023.2272644

  • Highly Pathogenic Avian Influenza A(H5N8) Clade 2.3.4.4b Virus in Dust Samples from Poultry Farms, France, 2021. Emerging Infectious Diseases, 28(7), 1446–1450. (2022). Filaire, F., Lebre, L., Foret-Lucas, C., et al. https://doi.org/10.3201/eid2807.212247

Other positions

OFFLU laboratory expert and Avian Technical Activity focal person, Food and Agriculture Organization of the United Nations (FAO).

Scholarships, grants, and awards

2024 Erasmus MC Young Investigator Grant (2025/2027)

My Groups