Dr. F.F. (Fabien) Filaire

After obtained an engineering degree in France in Biosciences, I completed a PhD in virology focused on the development of novel strategies for the early detection of highly pathogenic avian influenza viruses in poultry.

Then, I joined Prof. Herfst’s team in the Department of Viroscience as a postdoctoral researcher. My research focuses on viral and host factors involved in the airborne transmission of influenza A viruses, as well as cross-species transmission.

• 2013-2020: National Institute of Applied Science (INSA) Lyon, France, Biosciences Engineer
  
  
• 2020-2023: PhD student, Theseo France, Laval, France- Mixed Research Unit 1225 IHAP (Host-Pathogen Interaction) from the National Veterinary School of Toulouse (ENVT) and INRAe – The Engineering School of Toulouse, Platform TOAsT – PhD entitled: ‘Development of innovative field deployable and non-invasive strategies for early detection of high pathogenicity avian influenza viruses’.


• 2024- ongoing: Postdoctoral Researcher, Prof. Herfst group, Viroscience Department.

• Influenza A(H5N1) shedding in air corresponds to transmissibility in mammals. Nat Microbiol 10, 14–19 (2025). Tosheva, I.I., Filaire, F., Rijnink, W.F. et al. https://doi.org/10.1038/s41564-024-01885-6
  
  
• The highly pathogenic H5N1 virus found in U.S. dairy cattle has some characteristics that could enhance infection and transmission among mammals. Lab Anim. (2024). Filaire, F., Herfst, S. https://doi.org/10.1038/s41684-024-01425-z
  
  
• Viral shedding and environmental dispersion of two clade 2.3.4.4b H5 high pathogenicity avian influenza viruses in experimentally-infected mule ducks: implications for environmental sampling. Veterinary Research. (2024). Filaire, F.*, Bertan, K.*, Gaide, N., et al. https://doi.org/10.1186/s13567-024-01357-z
  
  
• High and low pathogenicity avian influenza virus discrimination and prediction based on volatile organic compounds signature by SIFT-MS: a proof-of-concept study. Scientific reports 14, 17051. (2024). Filaire, F., Sécula, A., Bessière, P., et al. https://doi.org/10.1038/s41598-024-67219-y
  
  
• Optimizing environmental viral surveillance: bovine serum albumin increases RT-qPCR sensitivity for high pathogenicity avian influenza H5Nx virus detection from dust samples. Microbiology Spectrum, 11(6), 1–9. (2023). Bessière, P., Hayes, B., Filaire, F., et al. https://doi.org/10.1128/spectrum.03055-23
  
  
• A real-time colourimetric reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for the rapid detection of highly pathogenic H5 clade 2.3.4.4b avian influenza viruses. Avian Pathology, 53(2), 93–100. (2024). Filaire, F., Sécula, A., Lebre, L., et al. https://doi.org/10.1080/03079457.2023.2276849
  
  
• The feather epithelium contributes to the dissemination and ecology of clade 2.3.4.4b H5 high pathogenicity avian influenza viruses in ducks. Emerging Microbes and Infections, 12(2). (2023). Gaide, N.*, Filaire, F.*, Bertan, K., et al. https://doi.org/10.1080/22221751.2023.2272644
  
  
• Highly Pathogenic Avian Influenza A(H5N8) Clade 2.3.4.4b Virus in Dust Samples from Poultry Farms, France, 2021. Emerging Infectious Diseases, 28(7), 1446–1450. (2022). Filaire, F., Lebre, L., Foret-Lucas, C., et al. https://doi.org/10.3201/eid2807.212247

OFFLU laboratory expert and Avian Technical Activity focal person, Food and Agriculture Organization of the United Nations (FAO).

2024 Erasmus MC Young Investigator Grant (2025/2027)