About
Introduction
Field(s) of expertise
- Overactive bladder.
- Underactive bladder.
- Urinary incontinence.
- Urodynamics.
- Sacral neuromodulation.
- Neurogenic bladder.
Education and career
1984 - 1991: Study of medicine, State University of Groningen.
1996: Doctoral degree on thesis Functional modelling of voiding, Erasmus University Rotterdam.
Recent Findings
Previous studies in the lab have shown that autologous dendritic cells pulsed with allogenic tumor cell lysate was able to induce peripheral T cell activation and tumor-reactive T cell responses in patients with mesothelioma and pancreatic cancer. Current research focuses on how to initiate an effective immune response in the tumor as well as the tumor-draining lymph node using dendritic cell vaccination. Furthermore, we are studying novel approaches for (personalized) vaccination. In addition, we have identified T cell characteristics that underlie clinical efficacy of immune check inhibitors or chemotherapeutic agents in mesothelioma. The selected publications below give an impression of our work.
Other positions
- Member of several professional organisations.
- Member of the editorial board of Neurourology and Urodynamics.
- Member of the EAU Guidelines panel on Neuro-Urology.
More
Clinical trials and studies
Experience as a sub-investigator in several clinical trials and studies on overactive bladder, underactive bladder, bladder pain syndrome and nocturia.