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Researcher

I.M.B.H. (Ingrid) van de Laar, MD, PhD

Principal Investigator

  • Department
  • Clinical Genetics
  • Focus area
  • My work focuses on identifying new genes and pathways involved in cardiovascular diseases, including aortic aneurysms, congenital heart defects, and cardiomyopathies.
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About I.M.B.H. (Ingrid) van de Laar, MD, PhD

Introduction

I am a clinical geneticist at Erasmus MC, where I enjoy combining patient care with research. Questions that arise in my outpatient clinic often inspire research projects aimed at finding answers for individuals and families with genetic disorders. Through this research, I strive to better understand the underlying mechanisms of these conditions and to contribute to the development of new strategies for therapeutic interventions.

Education and career

2002: MD, Utrecht University

2006: Clinical fellowship at the Center for Human Genetics, Leuven, Belgium

2009: Clinical Geneticist, board certified

2012: PhD, Erasmus University Rotterdam Thesis: ”Clinical and genetic studies in inherited cardiovascular malformations”

Publications

  • van den Bersselaar LM, van de Laar IMBH, Baars MJH, et al. Pregnancy and Delivery Outcomes in Vascular Ehlers-Danlos Syndrome: A Retrospective Multicentre Cohort Study. BJOG. 2025 Mar 19

  • Demirdas S, van den Bersselaar LM, Lechner R, et al. Vascular Ehlers-Danlos Syndrome: A Comprehensive Natural History Study in a Dutch National Cohort of 142 Patients. Circ Genom Precis Med. 2024 Jun;17(3):e003978

  • van den Bersselaar LM, Verhagen JMA, Bekkers JA et al. Expanding the genetic and phenotypic spectrum of ACTA2-related vasculopathies in a Dutch cohort. Genet Med. 2024 Feb;26(2):101024.

  • van de Laar IM, Oldenburg RA, Pals G et al.  Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis Nature Genetics 2011 Feb;43(2):121-

    Full list of publications

Teaching activities

2019: Judith M.A. Verhagen, PhD thesis: “Genetics of Cardiovascular Disorders”

Other positions

2025: Co-chair of MSA working VASCERN

  • Member of Working Group Cardiogenetics (VKGN)

  • Member of Working Group “Therapy genetic conditions” (VKGN)

Scholarships, grants, and awards

2006 Dekker grant for resident 9 (Dutch Heart Foundation)

2014 Dekker grant for junior medical specialist (Dutch Heart Foundation)

2015 Erasmus MC fellowship

My Groups

Cardiogenetics

Our research focuses on the clinical and genetic aspects of cardiovascular diseases - specifically cardiomyopathies and aortic aneurysms - to improve diagnostics and treatment.

Related

Departments and research centers

Genetic Identification logo

Clinical genetics

Research groups/labs

Cardiogenetics