Education and career
2008 to date Staff member/Assistant Professor, Dept. of Gastroenterology & Hepatology, Erasmus MC
2004-2007 Assistant Professor, Dept. of Pathology, Josephine Nefkens Institute, Erasmus MC
2003-2004 Research Scientist, Genentech, Inc., South San Francisco, CA.
1998-2002 Post-doc, Dept. of Human Genetics, University of Leiden, The Netherlands.
1994-1998 PhD-student, Dept. of Human Genetics, University of Leiden, The Netherlands. Cum laude, January 24, 2002.
Teacher for Bachelor of Clinical Technology (TU Delft/Erasmus MC/Leiden University.
- Jul 2008-Oct 2012: Lalini Raghoebir; Balancing on Sox: Involvement of Sox2 in determination and maintenance of organ identity of the gastrointestinal tract
- Jun 2008-Dec 2012: Elvira Bakker; Novel Aspects of Wnt Signaling in intestinal development and cancer
- Sept 2013-June 2018: Wenhui Wang; Targeting Wnt/β-catenin signaling in Liver Cancers
- Sept 2015-June 2019: The mutant components of Wnt/β-catenin signaling in liver cancer
Scholarships, grants, and awards
NWO Dutch Research Council VIDI 2004-09: Cross-talk between receptor tyrosine kinases and ß-catenin signaling during tumor initiation and progression.
KWF Dutch Cancer Society 2005-2010: Cross-talk between receptor tyrosine kinases and β-catenin signaling in colorectal cancer.
Erasmus MC PhD grant 2016-2020: Unraveling mechanisms controlling mucus production in colorectal cancer: A prominent role for ATOH1.
Erasmus MC PhD grant 2008-2012: The role of SOX2 in intestinal development and the formation of mucinous colorectal cancer.
Erasmus MC pilot grant 2012-2014: Transcriptional read-through as mechanism to explain the CpG island methylator phenotype of colorectal cancer.