Mischa Hoogeman works as a licensed medical physicist at the Radiotherapy department of ErasmusMC and the Holland Proton Therapy Center (HollandPTC). Since 2015, he has been appointed Head of Medical Physics and since 2017 he has been appointed as Professor at the Erasmus University Rotterdam on High-Precision and Adaptive Radiotherapy. Since April 2018, he also holds the position as Head of Medical Physics of the HollandPTC and since 2019 Mischa Hoogeman has a part-time appointment as professor at the TU Delft (Department of Radiation Science & Technology).
The overarching aim of his research is to widen the therapeutic window by the development, implementation and evaluation of high-precision radiotherapy techniques. Supported by two projects of the Dutch Cancer Society, he lead the research group that developed and implemented a novel plan-of-the-day technique to accurately irradiate the highly-deformable target volume of cervical cancer patients. Current research aims to further improve this technique, translate it to Stereotactic Body Radiotherapy, and aims to clinically evaluate the benefit in terms of reduction in side effects and improved quality of life.
With the introduction of proton therapy in the Netherlands the focus of research has shifted to proton therapy. Research in this area includes developing online-adaptive proton therapy by near-real-time daily re-optimization of the treatment plan, quantifying the uncertainties during the delivery of proton therapy that may impair the theoretical benefit, and developing methods to account for those by designing robust treatment plans.
Field(s) of expertise
- High-precision adaptive radiotherapy and proton therapy
- Treatment planning for proton therapy
- Robust optimization and evaluation for proton therapy
- Online-adaptive radiotherapy and proton therapy
- Normal tissue complication modelling
- Deformable registration of medical images
- Stereotactic (Body) Radiation Therapy
Education and career
- Member of HollandPTC R&D Program Council and Executive Team
- Member of the scientific advisory committee of the Daniel den Hoed foundation
- Part-time professor at the TU Delft (Department of Radiation Science & Technology)