About our research group/lab
Targets for the future
The Sophia Children's Hospital offers a unique population of patients receiving tertiary care. Several clinical drugs trials have been performed in recent years. We plan to expand our involvement in these drug trials with hospital pharmacists as co-investigators in this successful research line (in collaboration with dr. Sinno Simons and prof. Irwin Reiss). Pharmacists and clinical pharmacologists can also contribute substaintially to the rational and safe prescribing of (off-label) drugs in neonatal intensive care. We are planning trials with the 3D printing of medication, and minitablets.
Prof. dr. Karel Allegaert will be part of this research line.
- Precision Dosing of Doxapram in Preterm Infants Using Continuous Pharmacodynamic Data and Model-Based Pharmacokinetics: An Illustrative Case Series.
Poppe JA, van Weteringen W, Sebek LLG, Knibbe CAJ, Reiss IKM, Simons SHP,Flint RB.Front Pharmacol. 2020 May 12;11:665. doi: 10.3389/fphar.2020.00665. eCollection 2020.PMID: 32477133
- Pregnancy related pharmacokinetics and antimicrobial prophylaxis during fetal surgery, cefazolin and clindamycin as examples.
Allegaert K, Muller AE, Russo F, Schoenmakers S, Deprest J,Koch BCP.Prenat Diagn. 2020 May 22. doi: 10.1002/pd.5753. Online ahead of print.PMID: 32441341