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Research group/lab  |  B. Pullens, PhD

Laryngotracheal stenosis

Acquired pediatric laryngotracheal stenosis (LTS) is a rare but life-threatening disease which usually occurs after a prolonged period of intubation.

About our research group/lab

Our research

Background information

Despite the innovations and advances that have been made over the years, the management of pediatric LTS still proves to be very challenging for pediatric otolaryngologists. There is a lack of long-term outcome reporting and uncertainty on the best way to objectively evaluate the reconstructed airway. Furthermore, it is unknown what surgical and patient factors are associated with long-term outcome.

Overall aim

The aim is to evaluate surgical outcome for acquired pediatric LTS. By evaluating our outcome in a large surgical cohort, we hope to draw important conclusions on past treatment, make changes if necessary and improve our future outcome.

Research focus areas

Surgical cohort study, with prospective structured follow-up including visits at our outpatients clinic and for example regular endurance and pulmonary function testing.

Key Publications

Voice outcome and voice-related quality of life after surgery for pediatric laryngotracheal stenosis.
Pullens B, Hakkesteegt M, Hoeve H, Timmerman M, Joosten K. (2017). Laryngoscope. 2017 Jul;127(7):1707-1711.

Long-term quality of life in children after open airway surgery for laryngotracheal stenosis.
Pullens B, Dulfer K, Buysse CM, Hoeve LJ, Timmerman MK, Joosten KF. (2016). Int J Pediatr Otorhinolaryngol. 2016 May;84:88-93.

Long-term functional airway assessment after open airway surgery for laryngotracheal stenosis.
Pullens B, Pijnenburg MW, Hoeve HJ, Baatenburg de Jong RJ, Buysse CM, Timmerman MK, van der Schroeff MP, Joosten KF. (2016). Laryngoscope. 2016 Feb;126(2):472-7.


Collaborations within Erasmus MC

  • Department of Otorhinolaryngology (ENT).
  • Department of Pediatric Intensive Care.
  • Department of Neonatal Intensive Care.
  • Department of General Pediatrics.