Already 20 years ago, the first study on gene therapy for the bleeding disorder hemophilia B was published. Internist-hematologist Prof Dr Frank Leebeek explains what has happened since then. Is gene therapy the cure for the royal disease?
The omicron BA.1 variant of SARS-CoV-2 is less infectious in the brain and triggers less inflammation in brain cells than the virus variant responsible for the first SARS-CoV-2 wave. This has been shown in research with hamsters and human brain cells by scientists from the Erasmus MC. ‘Good news, but no guarantees for the future.’
One thing stands out about children with the rare SETD1B syndrome. More boys than girls have the disease, and boys are more severely affected. Scientist Kristina Lanko is on a quest to discover what causes this sex difference. ‘Brain cells are my favorite cells.’