About our department
Our mission is to innovate and optimise the diagnosis, treatment and prevention of severe mental health disorders in a medical context. The research conducted herein comprises applied, clinical and translational studies.
Detailed information about our research can be found on our website www.psych.nl.
Our scientific research is organized into three main research lines that are distinguished by their complementary methodological approaches.
The three research lines cooperate naturally. Applied Social and Forensic Psychiatry applies neurobiological (biomarker and genetic) approaches in collaboration with our laboratory of Neurobiology of Mood & Psychotic Disorders. Mood (and its medical perspectives) is also often a study focus area in the Medical Psychology research line.
Neurobiology of Mood & Psychotic Disorders
- The GEZIN (Genetische Zoektocht in Neuropsychiatrische stoornissen) study
- The OPPER (Onderzoeksprogamma Peripartum Psychiatrie Erasmus MC Rotterdam) study
Applied Social and Forensic Psychiatry
- Difficult-to-engage patients
- The iBerry study
- The UP’S study
- Forensic psychiatry
- Psychological aspects of living kidney donation
- Quality of life
Neurobiology of Mood & Psychotic Disorders:
Prof. dr. R.A. Ophoff
Dr. V. Bergink
Applied Social and Forensic Psychiatry:
(Separate website Department of Psychiatry Research)
The Department of Psychiatry makes use of the following Erasmus MC core facilities
Erasmus Centre for Animal Research (EDC)
The research group Neurobiology of Mood & Psychotic Disorders makes extensive use of the EDC facilities for the transgenic mouse modelling of psychiatric disorders, including behavioural, imaging and electrophysiological studies.
The Generation R Study
Multiple research lines within the department collaborate closely with the Generation R facility in areas such as the iBerry study. The research group Neurobiology of Mood & Psychotic Disorders participates in research on genomic data, brain imaging and mental health outcomes.
The Neurobiology of Mood & Psychotic Disorders group works closely with the genomics facility at the Erasmus MC for microarray genotyping, whole exome sequencing and RNA sequencing.
The research group Neurobiology of Mood & Psychotic Disorders collaborates closely with the iPS Facility in areas such as patient cellular reprogramming and neural lineage differentiation.
The faculty of Neurobiology of Mood & Psychotic Disorders has conducted several projects in collaboration with the Proteomics facility.
Regional and national collaborations
Dutch ministries expect University Medical Centers to play a regional and national coordinating role. This position provides us with the opportunity to involve other regional and national partners in our research, giving us the necessary financial and statistical critical mass to conduct our studies. Neurobiology of Mood & Psychotic Disorders has a strong national collaboration through the Institute for Human Organ and Disease Model Technologies. Here, prof. Kushner is the theme coordinator for brain-on-chip projects and member of the Netherlands Organ-on-Chip Initiative (NOCI) NOW Gravitation award consortium. Prof. van Busschbach has a strong history of cooperation with the Erasmus School of Health Policy and Management for the EQ-5D questionnaire and other quality of life research. Applied Social and Forensic Psychiatry has extensive collaboration with regional mental health care providers, which offers strong academic support for regional community mental health centers.
We have built a strong collaborative network of institutes. Kings College London and the University of Oslo are important partners in the prevention of coercion and outpatient psychiatry, while the University of Sydney collaborates with us on the Mental Health Living Longer Project. Moreover, we participate in a large international consortium (ICHOMS) for determining internationally-standardised criteria for key performance indicators for psychosis. We work closely with scientists from the Champalimaud Foundation Neuroscience Program (Lisbon) on advanced methodologies for in vivo imaging, with Columbia University (New York, USA) regarding functional genomic analyses, with Ben Gurion University (Israel) on the ascertainment of consanguineous families with Mendelian patterns of severe mental illness, and with the University of Toronto (Canada) on human-induced pluripotent stem cell modelling. Regarding peripartum psychiatry, we collaborate closely with Mount Sinai (New York, USA), the university of Aarhus (Denmark) and the NIH (Bethesda, USA). Prof. Kushner also serves as the Netherlands representative to the Federation of the European Neuroscience Societies (FENS) Council, and has leading roles in several European Commission grants (PerMed, NEURON and FET-CONNECT). Prof. van Busschbach is the chair of the international EuroQol Group, and leads research for the EQ-5D questionnaire.
(Seperate website Department of Psychiatry Research)