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Research project

Personalized Sports and Exercise as Medicine

Status: Ongoing

Personalizing exercise and sport via optimal loading, smart sensing, and tailored interventions to improve health in patients and athletes.

What we do

About our project

Why personalized sports & exercise as medicine?

Physical activity benefits health across the lifespan, yet many who need it most are least active (underloading); others are injured by overloading. We address this balance by tailoring loading to individual capacity.

 

Three pillars

We integrate medicine, engineering, data science and social sciences in three pillars: Optimal loading (capacity assessment), Smart sensing (real-world monitoring), and Effective intervention (behavior-focused implementation).

 

Two research lines

Research spans two lines: exercise in clinical populations and sports in healthy athletes. For patients with osteoarthritis, diabetes, cardiovascular disease, cancer survivorship, or long-COVID, we quantify load capacity, personalize prescriptions, and support long-term adherence using wearables and adaptive decision support in living-lab cohorts and pragmatic trials. In athletes, we model tissue load (IMUs/GPS, imaging, strength tests) to individualize training, prevent overuse, and guide return-to-sport via personalized feedback. Outputs include decision rules, normative datasets, and risk/response models that inform safe, effective activity across care and performance settings.

 

Expected impact

Personalized loading reduces adverse events, increases activity, and eases healthcare burden; results feed education and rapid clinical implementation via professional networks.

Our research focus

Optimal loading

We quantify individual load-bearing capacity using imaging (e.g., MRI/US), predictive musculoskeletal & cardiopulmonary simulations, disease knowledge and genetics to inform safe prescriptions.

 

Smart sensing

We develop minimally invasive wearables and smart textiles to capture daily physical and physiological load (e.g., IMUs, breathing/ECG, sweat biomarkers) for feedback and large cohort monitoring.

 

Effective intervention

We implement tailored programs with responsible, network-based behavior change strategies and real-time feedback, and test them in living-lab settings.

 

From lab to practice

A technical PhD advances models and sensors; a clinical PhD runs feasibility/intervention studies, ensures safe data handling, and drives implementation in care pathways

Funds & Grants

The Convergence Health & Technology – Flagship (pre-proposal) facilitated consortium formation.

The Consortium will search for additional grants and funding opportunities to be able to start this project.

Collaborations

Main collaborating institutions

Technical University (TU) Delft

Erasmus University Rotterdam (EUR)

 

Other participating institutions within Consortium

Eindhoven University of Technology (TU/e)

Amsterdam University Medical Center (Amsterdam UMC)

University of Twente

Maastricht University

Radboud University Medical Center (Radboud UMC)

Municipality of Rotterdam (City of Rotterdam)

Golazo Sports

Dutch Athletics Federation (AtletiekUnie)

NL Actief

Knowledge Centre for Sport & Physical Activity (Netherlands)

Sport Data Valley

Dutch Olympic Committee (NOC*NSF)

Our team

Principal investigators

Associate Professor R.J. de Vos
Associate Professor M. van Middelkoop
Assistant Professor E. van der Kruk

Team Leaders

C. Gunst
P. van den Bovenkamp

Team Members Consortium

M.S. Kleinsmann (TU Delft)
A. Seth (TU Delft)
T. Huysmans (TU Delft)
F.C.T. van der Helm (TU Delft)
H.E.J. Veeger (TU Delft)
K.M.B. Jansen (TU Delft)
F. Arroyo Cardoso (TU Delft)
J.J. Kraal (TU Delft)
S. Vos (TU/e)
T. Voortman (Erasmus MC)
J. Alsma (Erasmus MC)
J. van Meurs (Erasmus MC)
T. Wiggers (AtletiekUnie)
H.T. Jorstad (Amsterdam UMC)
K. Rohde (EUR – ESE)
P. Kocken (EUR – ESSB)
B. van Hooren (Maastricht University)
A. Karahanoglu (University Twente)
A. Bozzon (TU Delft)
E.E.M. Snijders (Gemeente Rotterdam)
S. Hofdom (Golazo)
R. Wouters (NL Actief)
C. Vervoorn (Kenniscentrum Sport & Bewegen)
M. van Beusekom (Sport Data Valley)
E. Visser (independent)
K. Maase (NOC*NSF)
T. Eijsvogels (Radboud UMC)
H. Koffijberg (University Twente)
A. Sciacchitano (TU Delft)
L. Lintmeijer (Sport Data Valley)
L. Bayoumi (Kenniscentrum Sport & Bewegen)

Postdoctoral Researchers and PhD candidates

to be appointed