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Leonard Schuele

L.P. (Leonard) Schuele

Junior Postdoc

  • Focus area
  • Clinical metagenomics, infectious disease, one health, pathogen genomics



Leonard is a junior postdoc at the Department of Viroscience. Here he applies high throughput sequencing approaches for:

i) genomic mpox virus surveillance throughout the Netherlands,

ii) viral exploration in the human-animal-environment interface, and

iii) antibody capture based metagenomic sequencing to reveal (novel) immunogenic viruses.

Field(s) of expertise

Application of Illumina and Nanopore sequencing in human, animal and environmental samples. Metagenomic and whole-genome sequencing with a focus on viral and bacterial pathogens.

Education and career

University hospital Tuebingen: Research assistant

University Medical Center Groningen: PhD, Application of Next-Generation Sequencing in Microbiology: From Clinical Diagnostics to One Health Surveillance

Erasmus MC: Junior postdoc, Department of Viroscience


Link to Leonard’s list of publications:

Circulation, viral diversity and genomic rearrangement in mpox virus in the Netherlands during the 2022 outbreak and beyond (https://doi.org/10.1002/jmv.29397)

Off-season circulation and characterization of enterovirus D68 with respiratory and neurological presentation using whole-genome sequencing (https://doi.org/10.3389/fmicb.2022.1088770)

Exploring a prolonged enterovirus C104 infection in a severely ill patient using nanopore sequencing (https://doi.org/10.1093/ve/veab109)

Evaluation of whole-genome sequence data analysis approaches for short- and long-read sequencing of Mycobacterium tuberculosis (https://doi.org/10.1099/mgen.0.000695)

First detection of porcine respirovirus 1 in Germany and the Netherlands (https://doi.org/10.1111/tbed.14100)

Critical steps in clinical shotgun metagenomics for the concomitant detection and typing of microbial pathogens (https://doi.org/10.1038/s41598-018-31873-w)

Expansion of Vancomycin-Resistant Enterococcus faecium in an Academic Tertiary Hospital in Southwest Germany: a Large-Scale Whole-Genome-Based Outbreak Investigation (https://doi.org/10.1128/aac.01978-18)

Teaching activities

Trainer and organization for: Practical Introduction to Next-Generation Sequencing using Oxford Nanopore's MinION Platform for Microbiologists and Public Health Professionals, Huye, Rwanda, 2024.

Scholarships, grants, and awards

  • Food Pro-tec-ts
  • European Union’s Horizon 2020 research and innovation programme (713660)
  • The German Center for Infection Research
  • The Beatrixoord Noord-Nederland Foundation
  • EurHealth-1Health