The focus of the mycobacterial research group of the department of medical microbiology and infectious diseases is to improve the treatment of mycobacterial infections including tuberculosis and infections with nontuberculous mycobacteria. To this aim we assess the activity and efficacy of different novel antimycobacterial drug (regimens) using a combination of different preclinical models including the in vitro time-kill kinetics assay and hollow fiber infection model, the ex vivo intracellular infection model as well as the murine tuberculosis model. By combining the results of these different assays we aim to improve the predictive value of preclinical antimycobacterial drug evaluation.
Publications of Jurriaan de Steenwinkel can be found at PubMed
- Daily supervising and teaching of residents Microbiology, residents Internal Medicine or Infectious disease specialist in training, Erasmus MC
- Lectures during the research master Infection and Immunity, Erasmus MC
- Lectures during the second year of the medicine students on Microbiology
- Supervising master Infection and Immunity students during their research projects, Erasmus MC