My PhD-project focusses on the use of whole genome sequencing (WGS) technology to explain unsolved cases of neurodevelopmental disorders in clinical genetics. I study novel disease candidate genes and non-coding causes of disease, from both case studies in our own patient cohort and population-based studies such as the 100K Genomics England project.
Education and career
BSc and MSc: Embryonic engineering at Northwest A&F University
- Identification and characterization of ERV transcripts in goat embryos.
Ruizhi Deng, Chengquan Han, Lu Zhao, Qing Zhang, Beifen Yan, Rui Cheng, Biao Wei, Peng Meng, Tingchao Mao, Yong Zhang, Jun Liu. (2019). Reproduction. 2019 Jan;157(1):115-126. doi: 10.1530/REP-18-0336.
- Overexpression of Tet3 in donor cells enhances goat somatic cell nuclear transfer efficiency.
Chengquan Han, Ruizhi Deng, Tingchao Mao, Yan Luo, Biao Wei, Peng Meng, Lu Zhao, Qing Zhang, Fusheng Quan, Jun Liu, Yong Zhang. (2018). FEBS J. 2018 Jul;285(14):2708-2723. doi: 10.1111/febs.14515. Epub 2018 Jun 8.