About our department
The main focus of the department is to understand the molecular mechanisms of gene regulation that underpin development and disease. Our research is mainly concentrated in the groups of Tokameh Mahmoudi, Jeroen Demmers and Peter Verrijzer. The Mahmoudi lab studies the role of chromatin regulation in HBV and HIV latency, its impact on pathologies, and novel therapeutic interventions. Jeroen Demmers heads the Erasmus MC proteomics facility that services the whole Erasmus MC community. In addition, his own research concentrates on the function of the ubiquitin-proteasome system (UPS) in health and disease. Verrijzer’s lab current research is aimed at understanding the coupling between cellular metabolism and epigenetics. In addition, they have a long-standing interest in the role of ATP-dependent chromatin remodelers in development and in human cancer.
C. Peter Verrijzer, head of department
Dept. of Biochemistry, room Ee642
Erasmus University Medical Center
Dr Molewaterplein 50
3015 GE Rotterdam