About our Department
Our research
What is the overall aim?
The mission of the department of Cardiology is to make a significant scientific contribution to reduce the burden of cardiovascular disease by 25% over the next 5-10 years. We aim to achieve this by performing translational research, clinical studies and population-based research in close collaboration with (inter)national partners and patient advocacy groups focusing on the key areas ischemic cardiovascular disease, congenital or acquired structural heart disease and as final common pathways arrhythmias and heart failure.What are the focus areas of your research? (examples)
The department of Cardiology performs translational research, clinical studies, and population-based research in close collaboration with (inter)national partners and patient advocacy groups on 5 key areas: Ischemic cardiovascular disease, congenital or acquired structural heart defects, arrhythmias and heart failure.Principal Investigators
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Prof. dr. R.A. De Boer
Head of department Cardiology
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Prof. dr. ir. H. (Eric) Boersma, PhD
Head of Cardiovascular Epidemiology
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Prof. dr. D.J.G.M. (Dirk-Jan) Duncker
Professor of Experimental Cardiology
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Prof. dr N.M.S. (Natasja) de Groot, PhD
Cardiologist-Electrophysiologist, chief Research Unit Translational Electrophysiology
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Prof. dr. N.M.D.A. (Nicolas) Van Mieghem, MD PhD
Head of Interventional Cardiology
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Prof dr. J.W. (Jolien) Roos-Hesselink, MD PhD
Head of Congenital Cardiology
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Prof. dr. ir A.F.W. (Ton) van der Steen, PhD
Head of Biomedical Engineering
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Prof. dr. P.P.T. (Peter) de Jaegere, MD PhD
Professor Interventional Cardiology
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Prof. dr. ir N. (Nico) de Jong, PhD
Professor Biomedical Engineering
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Prof. dr. M. (Daphne) Merkus, PhD
Professor of Cardiopulmonary Pathophysiology
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Prof. dr. G. (Gijs) van Soest, PhD
Head of Invasive Imaging
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Dr.ir. J.G. (Hans) Bosch, PhD
Associate Professor
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Dr. A.E. (Annemien) van den Bosch, MD
Associate professor, Congenital Cardiologist
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Dr. C. (Caroline) Cheng, PhD
Associate professor
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Dr. ir. F.J.H. (Frank) Gijsen, PhD
Associate Professor
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Dr. K. (Kim) van der Heiden, PhD
Associate professor
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Dr. K. (Klazina) Kooiman, PhD
Associate professor, Head of Therapeutic Ultrasound Contrast Agents
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Dr. O.C. (Olivier) Manintveld, MD
Associate professor
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Dr. ir. H.J. (Rik) Vos, PhD
Associate Professor
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Dr. ir. J.J. (Jolanda) Wentzel, PhD
Associate professor, Head of Biomechanics Laboratory
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Dr. K.M. (Martijn) Akkerhuis, MD
Cardiologist
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Dr.ir. A.C. (Ali) Akyildiz, PhD
Assistant professor
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Dr. H.M.M. (Heleen) van Beusekom, PhD
Assistant professor
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Prof. Dr. J.J. (Jasper) Brugts, MD
Professor, Cardiologist
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Dr. J. (Joost) Daemen, MD PhD
Interventional Cardiologist
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F. (Francis) Kalloor Joseph, PhD
Assistant Professor
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Prof. dr. I. (Isabella) Kardys, MD PhD
Cardiovascular Epidemiologist
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Dr. K.R. (Kirby) Lattwein, PhD
Assistant professor
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Dr. M. (Michelle) Michels, MD
Cardiologist
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Dr. O.E. (Oana) Sorop, PhD
Assistant professor
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Dr. ir. J.D. (Jason) Voorneveld, PhD
Assistant Professor
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Principal investigator dr. S.C. Yap, MD, PhD
Cardiac Electrophysiologist
Research lines
The department of Cardiology has 7 research groups which are all focused on 1 or more of the 5 key areas and are highly interconnected.
- Experimental Cardiology - Prof. dr. Dirk Jan Duncker
- Electrophysiology - Prof. dr. Natasja de Groot
- Cardiovascular Epidemiology - Prof. dr. Eric Boersma
- Congenital Cardiology - Prof. dr. Jolien Roos-Hesselink
- Intervention Cardiology - Prof. dr. Nicolas van Mieghem
- Heart Failure - Prof. dr. Jasper Brugts
- Biomedical Engineering - Prof. dr. ir. Ton van der Steen
Projects
4D-Flow Echocardiography for Diastolic Functional Imaging of the Left Ventricle
AMPHORA – Acoustic markers for enhanced remote sensing of radiation doses
Biomechanics and Atherosclerosis
Biomechanics and congenital cardiovascular disease
Biomechanics in Congenital Cardiology
BUBBLE CURE
BUBBLE QUEST
Cardiac Mechanics
EFFECTS - Echocardiographic Tissue Stiffness measurements
FUSION study: Coronary CT with FFRct
Human disease model for atherosclerosis
Imaging atherosclerotic plaque lipidomics in vivo
MIFFY- Monitoring infant brain perfusion by echography
Molecular imaging of atherosclerosis
MRAME – Mixed Reality Supporting Advanced Medical Education
PARFAIT
QUANTO-3D-myocardial-perfusion-imaging-with-echography
Rapid Innovation of Minimally Invasive Instruments
Seeing the heart attack (and more) before it happens
Theranostic-phospholipid-coated-ultrasound-contrast-agents
ULTRA-X-TREME X-Flow
Facilities
- a unique experimental intervention room, allowing state of the art cardiovascular intervention studies in human-sized pigs
- facilities for cardiovascular histopathology and molecular biology research, a scanning electron microscope
- own biobanking infrastructure within the Triallab of the Clinical Chemistry department
- a fast framing digital camera for up to 20 Million frames per seconds recordings, which is coupled to a custom-designed confocal microscope
- two optical labs, an ultrasound lab, facilities for MALDI imaging and a lab for cell culturing
- CUBE research facility for functional ultrasound brain imaging
Collaborations
- Many departments in the Erasmus MC
- The 16 Cardiovascular ACEs
- Dutch Cardiovascular Alliance
- TU Delft
- Netherlands Heart Institute