About our research group/lab
At Biomedical Engineering, for over 50 years now, engineers, scientists, clinicians, and companies team up to address the challenging task of diagnosis, treatment, and monitoring of cardiovascular diseases. The group, part of the Cardiology department of Erasmus MC, forms a strong multidisciplinary team to develop novel diagnostic and treatment strategies. The work covers the entire pathway from basic concepts and modelling to laboratory work, patient studies, and commercialization.
What is the overall aim?
Imaging, modelling and data interpretation stand at the basis of disease diagnosis, treatment, therapy guidance and monitoring, such that clinicians can provide better prognosis for the patient. We aim to develop and study unprecedented techniques to image the cardiovascular system and improve treatment of the patient.
What type of research do you focus on in this group?
The body contains many dynamics, e.g. the heart motion and blood flow, but also biological interactions between cells and their environment. We study and predict these complex dynamics, through state-of-the-art (and beyond) high frame rate techniques, thus being able to show the phenomena in slow-motion. For this, we build and use volumetric transducers and systems for echography, camera systems for in vitro visualization, and advanced computer models to predict and analyze the physics and biology underlying the phenomena. We challenge ourselves to develop the imaging, understand and model the physics and biology, improve the signal processing, and interpret the results with clinicians to provide actual information needed for better treatment of patients.
Within Biomedical engineering there are four research themes:
- Catheter based imaging,
- High frame rate ultrasound,
- Cardiovascular Biomechanics
- Ultrasound contrast agents.
Voorneveld et al., High-Frame-Rate Echo-Particle Image Velocimetry Can Measure the High-Velocity Diastolic Flow Patterns (2019)
Hoogendoorn et al, “Variation in Coronary Atherosclerosis Severity Related to a Distinct LDL (Low-Density Lipoprotein) Profile: Findings From a Familial Hypercholesterolemia Pig Model” (2019)
Strachinaru et al., “Naturally Occurring Shear Waves in Healthy Volunteers and Hypertrophic Cardiomyopathy Patients” (2019)
Visscher et al. “Data Processing Pipeline for Lipid Profiling of Carotid Atherosclerotic Plaque with Mass Spectrometry Imaging” (2019)
Iskander-Rizk et al., “Photoacoustic imaging for guidance of interventions in cardiovascular medicine” (2019)
We work within several local, national and international frameworks:
- Medical Delta
- Dutch Society of Medical Ultrasound
- Dutch Royal Academy of Science
- World federation for ultrasound in medicine and biology
- IEEE Ultrasonics, Ferroelectrics and Frequency Control Society
- International Contrast Ultrasound Society
Within Biomedical Engineering, we are organizing 3 international annual conferences:
- The International Symposium on Biomechanics in Vascular Biology and Cardiovascular Disease
- Optics in Cardiology
- The European symposium on Ultrasound Contrast Imaging and therapy
Funding & Grants
The group is well-funded with grants from many sources.
These include Open Technology projects and personal grants from the Dutch Research Council (NWO), public-private partnership grants such as the Medical Delta and a NWO/Dutch Heart Foundation grant, Open and Personal grants from the European Research Council, and many local initiatives such as the TU Delft/Erasmus MC Convergence, and the Erasmus MC fellowship. See specific pages per subgroup.
The group hosts a NWO PIONIER, A Simon Stevin Master, 2 ERC laureates, 3 Veni’s, 3 Vidi’s, 1 Vici and a marie curie fellow.
Prof.dr.ir. N (Nico) de Jong
Dr.ir. A.C. (Ali) Akyildiz
Gerard van Burken
Kim van Gaalen
prof.dr.ir. PhD A.F.W. van der Steen
Head Biomedical Engineering Thorax Centre
Prof. J.G. Bosch
PhD K. Kooiman
PhD J.J. Wentzel
PhD G. van Soest
Dr.ir. F. Gijsen
Dr. K. van der Heiden
PhD and MSc H.J. Vos
PhD T. Wang
(principal investigator): Assistant Professor