Publication by Rory de Vries, Rik de Swart, Katharina Schmitz, Danny Noack, Bart Haagmans, Sander Herfst and Barry Rockx
Daily intranasal administration to ferrets completely prevented SARS-CoV-2 direct-contact transmission during 24-hour co-housing with infected animals, under stringent conditions that resulted in infection of 100% of untreated animals. These lipopeptides are highly stable and thus may readily translate into safe and effective intranasal prophylaxis to reduce transmission of SARS-CoV-2.
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